Evaluation of a unique bovine collagen matrix for soft tissue repair and reinforcement

Veritas(R) Collagen Matrix, a product of Synovis Surgical Innovations, is derived from bovine pericardium. It can be used for a number of applications including body wall repair and replacement. In this study, we evaluated its efficacy as an adhesion barrier in a rabbit model of uterine horn surgery. When Veritas(R) was placed on the uterine horn stump it reduced the incidence of adhesions by 50% (n.s.) compared with untreated controls. Histologic analysis of recovered material showed that the surface was covered with a monolayer of mesothelial-like cells. In addition, there was an infiltration of host cells into the matrix of the product, which suggests a replacement of the material with host tissue.