Changes in physical activity and risk of fracture: a Korean nationwide population-based cohort study

被引：23

作者：

Han, Sangsoo ^{[1
]}

Jang, Hae-Dong ^{[2
]}

Choi, Sungwoo ^{[1
]}

Kim, Gi Deok ^{[2
]}

Han, Kyungdo ^{[3
]}

Lim, Hyunwoong ^{[4
]}

Koo, Bongmo ^{[5
]}

Min, Kyung Dae ^{[2
]}

Hong, Jae-Young ^{[5
]}

机构：

[1] Soonchunhyang Univ, Dept Emergency Meidcine, Bucheon Hosp, 170 Jomaru Ro, Bucheon 14584, South Korea

[2] Soonchunhyang Univ, Dept Orthopaed Surg, Bucheon Hosp, 170 Jomaru Ro, Bucheon 14584, South Korea

[3] Catholic Univ, Dept Biostat, Coll Med, 296-12 Changgyeonggung Ro, Seoul 03083, South Korea

[4] Korea Univ, Dept Ind Management Engn, Seoul 02841, South Korea

[5] Korea Univ Hosp, Dept Orthoped, 123 Jeokgeum Ro, Ansan 15355, Gyeonggi Do, South Korea

来源：

SCIENTIFIC REPORTS | 2020年 / 10卷 / 01期

关键词：

OLDER-ADULTS; HIP FRACTURE; DISEASE RISK; BONE; EXERCISE; OSTEOPOROSIS; QUESTIONNAIRE; ASSOCIATION; MORTALITY; STRENGTH;

D O I：

10.1038/s41598-020-73495-1

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Physical activity (PA) is one of the most important modifiable factors associated with fracture risk. However, the association between interval changes in PA and the risk of fracture remains unknown. We investigated the risk of fracture development according to interval changes in PA in middle aged and older individuals. In this nationwide cohort study of adults aged >= 40 years, more than 4.9 million individuals without fractures within the last year who underwent two consecutive national health screenings in Korea from 2009 to 2012 were identified. The risk of fracture between 2013 and 2016 according to interval changes in regular PA was prospectively analyzed. Compared to individuals with a continuous lack of PA, those with a decrease in PA (0.41/1000 person-years (PY) decrease in incidence rate (IR); adjusted hazard ratio (aHR) 0.975; 95% confidence interval (CI) 0.964-0.987), increase in PA (1.8/1000 PY decrease in IR; aHR 0.948; 95% CI 0.937-0.959), and continuous PA (3.58/1000 PY decrease in IR; aHR 0.888; 95% CI 0.875-0.901) had a significantly reduced risk of fracture. Interval changes in regular PA were associated with risk of fracture. Individuals who engaged in continuous regular PA exhibited the maximum protective benefit against fracture.

引用

页数：9

共 40 条

[1] CONTRASTS IN MUSCLE AND MYOFIBERS OF ELITE MALE AND FEMALE BODYBUILDERS [J].