Voltage-gated Ca2+ channel proteins do not function as ion channels in T cells

被引：1
|
作者：
Cahalan, Michael D. [1 ,2 ]
机构：
[1] Univ Calif Irvine, Dept Physiol & Biophys, Irvine, CA 92697 USA
[2] Univ Calif Irvine, Inst Immunol, Irvine, CA 92697 USA
来源：
SCIENCE SIGNALING | 2022年 / 15卷 / 738期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1126/scisignal.abq5594
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Calcium (Ca2+) signaling has long been known to be crucial for T cell activation. Erdogmus et al. tested the function of voltage-gated Ca2+ channel (CaV) proteins and discovered a nonchannel function mediated by an accessory subunit but found no evidence for CaV channel activity in T cells.
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页数：3
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