Spatially resolved transcriptomics adds a new dimension to genomics

被引：189

作者：

Larsson, Ludvig ^{[1
]}

Frisen, Jonas ^{[2
]}

Lundeberg, Joakim ^{[1
]}

机构：

[1] KTH Royal Inst Technol, Dept Gene Technol, Sci Life Lab, Stockholm, Sweden

[2] Karolinska Inst, Dept Cell & Mol Biol, Stockholm, Sweden

来源：

NATURE METHODS | 2021年 / 18卷 / 01期

关键词：

GENE-EXPRESSION; TISSUE;

D O I：

10.1038/s41592-020-01038-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

As single-cell omics continue to advance, the field of spatially resolved transcriptomics has emerged with a set of experimental and computational methods to map out the positions of cells and their gene expression profiles in space. Here we summarize current transcriptome-wide and sequencing-based methodologies and their applications in genomics research.

引用

页码：15 / 18

页数：4

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