Evaluation of linear lesion formation and thermodynamics by dragging ablation with the third-generation laser balloon

被引：3

作者：

Nagase, Takahiko ^{[1
]}

Asano, So ^{[1
]}

Fukunaga, Hiroshi ^{[1
]}

Kasai, Yuhei ^{[1
]}

Inoue, Kanki ^{[1
]}

Sekiguchi, Yukio ^{[1
]}

Tanizaki, Kohei ^{[1
]}

Murai, Tatsuya ^{[2
]}

Nanasato, Mamoru ^{[1
]}

Umemura, Jun ^{[1
]}

Nitta, Junichi ^{[1
]}

Isobe, Mitsuaki ^{[1
]}

机构：

[1] Sakakibara Heart Inst, Dept Cardiol, Tokyo, Japan

[2] Sakakibara Heart Inst, Dept Pathol, Tokyo, Japan

来源：

HEART RHYTHM O2 | 2022年 / 3卷 / 03期

关键词：

Atrial fibrillation; Linear lesion formation; Point-by-point ablation; RAPID mode ablation; Third-generation laser; balloon; PULMONARY; MULTICENTER;

D O I：

10.1016/j.hroo.2022.04.001

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BACKGROUND The lesion formation properties of a motorized rotational delivery (RAPID) mode, third-generation laser balloon (LB3) ablation compared to point-by-point laser ablation in patients with atrial fibrillation remain unclear. OBJECTIVE The purpose of this study was to assess lesion characteristics and thermodynamics in LB3 ablation with a RAPID mode in vitro model. METHODS Chicken muscles were cauterized using LB3 in RAPID mode with 13 W and 15 W and 50% overlapped point-by-point fashion with 7 W/30 seconds, 8.5 W/20 seconds, 10 W/20 seconds, and 12 W/20 seconds. Lesion depth, width, and continuity were compared. Lesion continuity was classified by the visible gap degree categorized from 1 (perfect) to 3 (poor). Thermodynamics and maximum tissue temperatures were assessed under infrared thermographic monitoring. Fifteen and 5 lesions were evaluated per ablation protocol for measurement of lesion size and continuity and for thermographic assessment, respectively. RESULTS Lesion depth and width were smaller in RAPID mode laser ablation than point-by-point laser ablation (P <.001). However, RAPID mode laser ablation revealed sufficient mean lesion depth of 5 mm or more. Lesion continuity was 1 (perfect) in all samples in RAPID mode laser ablation and point-by-point laser ablation (P = 1). Infrared thermographic observation demonstrated fast and gapless linear lesion formation with thermal stacking in RAPID mode laser ablation. Maximum tissue temperature was lower in RAPID mode laser ablation than point-by-point laser ablation (P <.001). CONCLUSION RAPID mode LB3 ablation could provide fast, gapless, and acceptable lesion formation with thermal stacking and moderate tissue temperature rise.

引用

页码：311 / 318

页数：8