Clinical features and outcomes of tetanus: a retrospective study

被引:23
作者
Fan, Zhe [1 ,2 ]
Zhao, Yue [3 ]
Wang, Shuang [3 ]
Zhang, Feng [4 ]
Zhuang, Chengjun [5 ]
机构
[1] Dalian Med Univ, Dept Gen Surg, Peoples Hosp Dalian 3, Dalian, Peoples R China
[2] Southeast Univ, Sch Med, Zhongda Hosp, Dept Gen Surg, Nanjing, Jiangsu, Peoples R China
[3] Dalian Med Univ, Grad Sch, Dalian, Peoples R China
[4] Dalian Med Univ, Dept Gen Surg, Affiliated Hosp 2, 467 Zhongshan Rd, Dalian 116023, Peoples R China
[5] Dalian Med Univ, Dept Crit Care Med, Affiliated Hosp 2, 467 Zhongshan Rd, Dalian 116023, Peoples R China
基金
中国国家自然科学基金;
关键词
tetanus; intensive care unit; retrospective study; INTENSIVE-CARE-UNIT; IMMUNIZATION; MANAGEMENT; DIPHTHERIA; PERTUSSIS; MORTALITY;
D O I
10.2147/IDR.S204650
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Background: Tetanus is a serious disease resulting in muscle spasm, and even death. Methods: A retrospective, single-center study was conducted by analyzing demographic and clinical parameters. Results: The study included 12 males (70.6%) and 5 females (29.4%). The mean age of the patients was 56.71 +/- 9.05 years. Patient occupations included farming (47.0%), retired (23.5), homebound (23.5), and workers (6.0%). The causes of patient injuries were as follows: metal injury (52.9%), deep injury (29.4%), electrical injury (5.9%), maxillofacial region and knee injury (5.9%), and skin ulceration (5.9%). The disease duration ranged from 3 to 36 days, and the mean incubation period was 12.65 +/- 10.17 days. Four patients had co-morbidities. The infected patients were given tetanus antitoxin (TAT) and antibiotics treatment. One patient was given continuous renal replacement therapy (CRRT) and only one patient died. Conclusions: In our department, although tetanus is a serious disease, with effective treatment, patients have reasonable cure and low death rates.
引用
收藏
页码:1289 / 1293
页数:5
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