Electrochemical fingerprint of street samples for fast on-site screening of cocaine in seized drug powders

被引:99
作者
de Jong, Mats [1 ,3 ]
Sleegers, Nick [1 ]
Kim, Jayoung [2 ]
Van Durme, Filip [3 ]
Samyn, Nele [3 ]
Wang, Joseph [2 ]
De Wael, Karolien [1 ]
机构
[1] AXES Res Grp, Dept Chem, Groenenborgerlaan 171, B-2020 Antwerp, Belgium
[2] Univ Calif San Diego, Dept Nanoengn, La Jolla, CA 92093 USA
[3] NICC, Vilvoordsesteenweg 100, B-1120 Brussels, Belgium
关键词
GLASSY-CARBON ELECTRODE; VOLTAMMETRIC DETERMINATION; MECHANISM; SERUM; ACID;
D O I
10.1039/c5sc04309c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report on a wearable fingertip sensor for on-the-spot identification of cocaine and its cutting agents in street samples. Traditionally, on-site screening is performed by means of colour tests which are difficult to interpret and lack selectivity. By presenting the distinct voltammetric response of cocaine, cutting agents, binary mixtures of cocaine and street samples in solution and powder street samples, we were able to elucidate the electrochemical fingerprint of all these compounds. The new electrochemical concept holds considerable promise as an on-site screening method.
引用
收藏
页码:2364 / 2370
页数:7
相关论文
共 22 条
[1]   Sensitive and selective cocaine electrochemical detection using disposable sensors [J].
Asturias-Arribas, Laura ;
Asuncion Alonso-Lomillo, M. ;
Dominguez-Renedo, Olga ;
Julia Arcos-Martinez, M. .
ANALYTICA CHIMICA ACTA, 2014, 834 :30-36
[2]   Solid-state Forensic Finger sensor for integrated sampling and detection of gunshot residue and explosives: towards 'Lab-on-a-finger' [J].
Bandodkar, Amay J. ;
O'Mahony, Aoife M. ;
Ramirez, Julian ;
Samek, Izabela A. ;
Anderson, Sean M. ;
Windmiller, Joshua R. ;
Wang, Joseph .
ANALYST, 2013, 138 (18) :5288-5295
[3]   Development of a voltammetric procedure for assay of the antihistamine drug hydroxyzine at a glassy carbon electrode: Quantification and pharmacokinetic studies [J].
Beltagi, A. M. ;
Abdallah, O. M. ;
Ghoneim, M. M. .
TALANTA, 2008, 74 (04) :851-859
[4]   Purity and adulterant analysis of crack seizures in Brazil [J].
Fukushima, Andre R. ;
Carvalho, Virginia M. ;
Carvalho, Debora G. ;
Diaz, Ernesto ;
Vega Bustillos, Jose Oscar William ;
Spinosa, Helenice de S. ;
Chasin, Alice A. M. .
FORENSIC SCIENCE INTERNATIONAL, 2014, 243 :95-98
[5]   Voltammetric determination of paracetamol at C60-modified glassy carbon electrode [J].
Goyal, RN ;
Singh, SP .
ELECTROCHIMICA ACTA, 2006, 51 (15) :3008-3012
[6]   DETERMINATION OF LIDOCAINE AND ACTIVE METABOLITES IN BLOOD-SERUM BY LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION [J].
HALBERT, MK ;
BALDWIN, RP .
JOURNAL OF CHROMATOGRAPHY, 1984, 306 (MAR) :269-277
[7]  
Lemahieu J. L., 2014, WORLD DRUG REPORT
[8]  
Mazzo D. J., 1994, ANAL PROFILES DRUG S, V23
[9]   Experimental and Computational Studies on the Electrochemical Oxidation of Caffeine at Pseudo Carbon Paste Electrode and Its Voltammetric Determination in Different Real Samples [J].
Mersal, Gaber A. M. .
FOOD ANALYTICAL METHODS, 2012, 5 (03) :520-529
[10]   Cocaine use and acute left ventricular dysfunction [J].
Missouris, CG ;
Swift, PA ;
Singer, DRJ .
LANCET, 2001, 357 (9268) :1586-1586