DAT positivity in blood donors: A perplexing scenario

被引:5
作者
Bedi, Ravneet Kaur [1 ]
Mittal, Kshitija [1 ]
Sood, Tanvi [1 ]
Kumar, Rakesh [1 ]
Praveen, Ajay S. [1 ]
机构
[1] Govt Med Coll & Hosp, Dept Transfus Med, Chandigarh, India
关键词
Direct antiglobulin test (DAT); Donors;
D O I
10.1016/j.transci.2013.09.017
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A blood request was received for 70 year male patient suffering from Chronic Obstructive Pulmonary Disease with anemia. One unit was found incompatible in AHG phase. Patient's antibody screen, indirect antiglobulin test (IAT), direct antiglobulin test (DAT) and auto control was negative. DAT of donor unit was positive with anti IgG gel card and negative with C3d reagent along with positive auto control. Donor was 30 year male with no history of blood transfusion and medication and had no evidence of hemolysis. Donors with positive DAT should be deferred, notified and referred to physician but further studies are required. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:239 / 241
页数:3
相关论文
共 10 条
[1]  
Bellia M, 2002, Immunohematology, V18, P78
[2]  
Freedman J, 1987, Transfus Med Rev, V1, P58, DOI 10.1016/S0887-7963(87)70006-6
[3]  
Garratty G, 1987, Transfus Med Rev, V1, P47, DOI 10.1016/S0887-7963(87)70005-4
[4]  
Issitt PD., 1998, APPL BLOOD GROUP SER, P1015
[5]  
Judd WJ, 1999, DIRECT ANTIGLOBULIN
[6]  
Kaplan H.S., 1985, Diagn. Med, V8, P29
[7]  
Petz LD., 2004, Immune Hemolytic Anemias, V2nd
[8]   Blood donors with positive direct antiglobulin tests are at increased risk for cancer [J].
Rottenberg, Yakir ;
Yahalom, Vered ;
Shinar, Eilat ;
Barchana, Micha ;
Adler, Bella ;
Paltiel, Ora .
TRANSFUSION, 2009, 49 (05) :838-842
[9]  
WEINER W, 1965, BIBL HAEMATOL, P35
[10]   The role of the Coombs test in evaluating hemolysis in adults [J].
Zarandona, JM ;
Yazer, MH .
CANADIAN MEDICAL ASSOCIATION JOURNAL, 2006, 174 (03) :305-307