REM sleep behavior disorder in Parkinson's disease

被引：2
|
作者：
Muntean, Maria-Lucia [1 ,2 ]
Sixel-Doering, Friederike [1 ]
Trenkwalder, Claudia [1 ,3 ]
机构：
[1] Paracelsus Elena Klin, D-34128 Kassel, Germany
[2] Univ Med & Pharm, Dept Neurosci, Cluj Napoca 400012, Romania
[3] Univ Gottingen, Dept Neurosurg, D-37075 Gottingen, Germany
来源：
JOURNAL OF NEURAL TRANSMISSION | 2014年 / 121卷
关键词：
REM sleep behavior disorder (RBD); Parkinson's disease; Polysomnography; DELAYED EMERGENCE; COGNITIVE IMPAIRMENT; DEMENTIA; MELATONIN; PATHOPHYSIOLOGY; DIAGNOSIS; FEATURES; UPDATE; RBD;
D O I：
10.1007/s00702-014-1192-4
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disorder characterized by loss of normal muscle atonia during REM sleep with recurrent dream enactment and excessive motor activity. It is a frequent feature in patients with Parkinson's disease (PD) and other alpha-synucleinopathies, and can occur at any stage of the disease. RBD could be considered a premotor clinical manifestation, and can antedate by many years the motor symptomatology. The prognostic value of RBD for the risk of developing PD still needs to be established. This review article focuses on the clinical aspects, screening and diagnostic criteria as well as therapeutic aspects of RBD in PD patients. Pathophysiological pathways are also briefly reviewed.
引用
收藏
页码：S41 / S47
页数：7
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