Is it true that coeliacs do not digest gliadin? Degradation pattern of gliadin in coeliac disease small intestinal mucosa

被引:31
|
作者
Bernardo, D. [1 ]
Garrote, J. A. [1 ,2 ]
Nadal, I. [3 ]
Leon, A. J. [1 ]
Calvo, C. [1 ,4 ]
Fernandez-Salazar, L. [5 ]
Blanco-Quiros, A. [1 ]
Sanz, Y. [3 ]
Arranz, E. [1 ]
机构
[1] Univ Valladolid, Dept Paediat & Immunol, Mucosal Immunol Lab, CSIC,IBGM, E-47005 Valladolid, Spain
[2] Hosp Clin Univ, Res Unit, Valladolid, Spain
[3] CSIC, Inst Agroquim & Tecnol Alimentos, E-46010 Valencia, Spain
[4] Hosp Clin Univ, Paediat Serv, Valladolid, Spain
[5] Hosp Clin Univ, Gastroenterol Serv, Valladolid, Spain
关键词
GLUTEN;
D O I
10.1136/gut.2008.167296
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:886 / 887
页数:2
相关论文
共 50 条
  • [1] IMMEDIATE EFFECTS OF GLIADIN ON INTESTINAL MUCOSA IN COELIAC DISEASE
    JOS, J
    ACTA PAEDIATRICA SCANDINAVICA, 1969, 58 (03): : 312 - &
  • [2] Is there a direct specific citotoxic effect of gliadin on the intestinal mucosa in coeliac disease?
    Auricchio, S
    Maiuri, L
    COELIAC DISEASE, 2003, : 23 - 27
  • [3] Gliadin and a gliadin derived peptide provoke oral mucosa in coeliac disease.
    Láhteenoja, H
    Toivanen, A
    Viander, M
    Räiha, I
    Vilja, P
    Mäki, M
    Syrjänen, S
    JOURNAL OF DENTAL RESEARCH, 2000, 79 (05) : 1301 - 1301
  • [4] Pattern of cytokine expression by treated coeliac intestinal mucosa upon in vitro gliadin challenge
    Maiuri, L
    Picarelli, A
    DeMarco, G
    Coletta, S
    Fuccio, A
    Greco, M
    DiGiovambattista, F
    Auricchio, S
    Londei, M
    GASTROENTEROLOGY, 1996, 110 (04) : A955 - A955
  • [5] Local challenge of oral mucosa with gliadin in patients with coeliac disease
    Lähteenoja, H
    Mäki, M
    Viander, M
    Toivanen, A
    Syrjänen, S
    CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2000, 120 (01): : 38 - 45
  • [6] T cells from the small intestinal mucosa of coeliac disease patients recognize a unique peptide sequence of gliadin.
    van de Wal, Y
    Kooy, Y
    van Veelen, P
    Peña, S
    Mearin, L
    Molberg, O
    Lundin, K
    Sollid, L
    Mutis, T
    Benckhuijsen, W
    Drijfhout, JW
    Koning, F
    GASTROENTEROLOGY, 1998, 114 (04) : A1105 - A1105
  • [7] Gliadin peptide specific intestinal T cells in coeliac disease
    Lundin, KEA
    Sollid, LM
    GUT, 2003, 52 (02) : 162 - 162
  • [8] Do gliadin and tissue transglutaminase mediate PPAR downregulation in intestinal cells of patients with coeliac disease?
    De Re, V.
    Simula, M. P.
    Notarpietro, A.
    Canzonieri, V.
    Cannizzaro, R.
    Toffoli, G.
    GUT, 2010, 59 (12) : 1730 - 1731
  • [9] Altered gliadin peptide binding to small intestinal brush border membranes in coeliac disease is independent of disease activity.
    Bolte, G
    Beuermann, K
    Stern, M
    GASTROENTEROLOGY, 1998, 114 (04) : A353 - A353