Effect of Spinal Anesthesia for Elective Cesarean Section on Cerebral Blood Oxygenation Changes: Comparison of Hyperbaric and Isobaric Bupivacaine

被引：10

作者：

Kondo, Yuko ^{[1
,2
]}

Sakatani, Kaoru ^{[3
]}

Hirose, Noriya ^{[2
]}

Maeda, Takeshi ^{[1
,2
]}

Kato, Jitsu ^{[2
]}

Ogawa, Setsuro ^{[2
]}

Katayama, Yoichi ^{[1
]}

机构：

[1] Nihon Univ, Sch Med, Dept Neurol Surg, Div Neurosurg,Itabashi Ku, Tokyo 1738610, Japan

[2] Nihon Univ, Sch Med, Dept Anesthesiol, Div Anesthesiol, Tokyo 1738610, Japan

[3] Nihon Univ, Sch Med, Dept Neurol Surg, Div Opt Brain Engn, Tokyo 1738610, Japan

来源：

OXYGEN TRANSPORT TO TISSUE XXXIV | 2013年 / 765卷

基金：

日本科学技术振兴机构;

关键词：

Cesarean; Bupivacaine; VOLUME;

D O I：

10.1007/978-1-4614-4989-8_16

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

We used near-infrared spectroscopy (NIRS) to evaluate cerebral blood oxygenation changes in subjects undergoing cesarean section under spinal anesthesia (SP) with hyperbaric bupivacaine (group H, 27 subjects) or isobaric bupivacaine (group I, 15 subjects). In group H, total-Hb, oxy-Hb, and mean blood pressure (MBP) within 20 min after SP were significantly lower than the baseline values. In contrast, there was no significant change from baseline in total-Hb, oxy-Hb, or MBP in group I after SP. Total-Hb and MBP in group H were significantly lower than those in group I within 10 min after SP. There was no significant change of deoxy-Hb, tissue oxygen index, or heart rate from baseline in either of the groups. These results suggest that isobaric bupivacaine may be superior to hyperbaric bupivacaine for preventing a decrease of maternal cerebral blood flow after SP for cesarean section.

引用

页码：109 / 114

页数：6

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