Select the best: novel biocatalysts for industrial applications

被引：13
|
作者：
Konarzycka-Bessler, Monika [1 ]
Jaeger, Karl-Erich [1 ]
机构：
[1] Univ Dusseldorf, Inst Mol Enzyme Technol, Res Ctr Juelich, D-52428 Julich, Germany
来源：
TRENDS IN BIOTECHNOLOGY | 2006年 / 24卷 / 06期
关键词：
D O I：
10.1016/j.tibtech.2006.04.004
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The number of biocatalysts needed for biotechnological applications is increasing rapidly, necessitating the development of novel identification systems. To date, strategies based on high-throughput screening and selection are applied, with the latter enabling a desired phenotype to survive under appropriate conditions. The groups of Witholt and de Lorenzo have devised a novel selection system, comprising a transcriptional regulator that is activated upon binding to the product of a biocatalytic reaction, which paves the way for easier selection of many different biocatalysts.
引用
收藏
页码：248 / 250
页数：3
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