Exchange transfusion to reverse severe pertussis-induced cardiogenic shock

被引:38
作者
Donoso, Alejandro F. [1 ]
Cruces, Pablo I. [1 ]
Camacho, Jorge F. [1 ]
Leon, Jose A. [1 ]
Kong, Jorge A. [1 ]
机构
[1] Padre Hurtado Hosp, Pediat Intens Care Unit, Santiago, Chile
关键词
Bordetella pertussis; pulmonary hypertension; exchange transfusion; hyperleukocytosis; PULMONARY-HYPERTENSION; INFANTS; HYPERLEUKOCYTOSIS; DEATHS;
D O I
10.1097/01.inf.0000232630.70138.a2
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Severe pertussis has a high mortality risk, especially in those with high white blood cell counts and pulmonary hypertension. Exchange transfusion can reduce the leukocyte mass in blood. We report 3 young infants with severe pertussis and hyperleukocytosis who developed cardiogenic shock and pulmonary hypertension. Exchange transfusion was performed. The white blood cell count decreased accompanied by improvement in the cardiopulmonary condition and survival in the 3 infants. Exchange transfusion should be considered in patients with severe pertussis with hyperleukocytosis.
引用
收藏
页码:846 / 848
页数:3
相关论文
共 13 条
[1]   CYTOREDUCTIVE PROCEDURES IN THE EARLY MANAGEMENT IN CASES OF LEUKEMIA AND HYPERLEUKOCYTOSIS IN CHILDREN [J].
BUNIN, NJ ;
KUNKEL, K ;
CALLIHAN, TR .
MEDICAL AND PEDIATRIC ONCOLOGY, 1987, 15 (05) :232-235
[2]   Bordetella pertussis infection causing pulmonary hypertension [J].
Casano, P ;
Odena, MP ;
Cambra, FJ ;
Martín, JM ;
Palomeque, A .
ARCHIVES OF DISEASE IN CHILDHOOD, 2002, 86 (06) :453-454
[3]   Pertussis and fatal pulmonary hypertension:: A discouraged entity [J].
Donoso, A ;
León, J ;
Ramírez, M ;
Rojas, G ;
Oberpaur, B .
SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES, 2005, 37 (02) :145-148
[4]   SEVERE PULMONARY-HYPERTENSION ASSOCIATED WITH SHOCK AND DEATH IN INFANTS INFECTED WITH BORDETELLA-PERTUSSIS [J].
GOULIN, GD ;
KAYA, KM ;
BRADLEY, JS .
CRITICAL CARE MEDICINE, 1993, 21 (11) :1791-1794
[5]  
GRZEZCZAK M, 2004, CRIT CARE MED, V32, pA182
[6]   Predictors of death in infants hospitalized with pertussis: A case-control study of 16 pertussis deaths in Canada [J].
Mikelova, LK ;
Halperin, SA ;
Scheifele, D ;
Smith, B ;
Ford-Jones, F ;
Vaudry, W ;
Jadavji, T ;
Law, B ;
Moore, D .
JOURNAL OF PEDIATRICS, 2003, 143 (05) :576-581
[7]   Is leukocytosis a predictor of mortality in severe pertussis infection? [J].
Pierce, C ;
Klein, N ;
Peters, M .
INTENSIVE CARE MEDICINE, 2000, 26 (10) :1512-1514
[8]  
Romano MJ, 2004, PEDIATRICS, V114, P264
[9]   Neonatal pertussis requiring extracorporeal membrane oxygenation [J].
Sreenan, CD ;
Osiovich, H .
PEDIATRIC SURGERY INTERNATIONAL, 2001, 17 (2-3) :201-203
[10]  
*US DEP HHS CTR DI, SUMM NOT DIS US