Oprozomib in patients with newly diagnosed multiple myeloma

被引:16
作者
Hari, Parameswaran [1 ]
Matous, Jeffrey V. [2 ]
Voorhees, Peter M. [3 ]
Shain, Kenneth H. [4 ]
Obreja, Mihaela [5 ]
Frye, John [5 ]
Fujii, Hisaki [5 ]
Jakubowiak, Andrzej J. [6 ]
Rossi, Davide [7 ]
Sonneveld, Pieter [8 ]
机构
[1] Med Coll Wisconsin, Milwaukee, WI 53226 USA
[2] Colorado Blood Canc Inst, Denver, CO USA
[3] Atrium Hlth, Levine Canc Inst, Charlotte, NC USA
[4] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[5] Amgen Inc, Thousand Oaks, CA 91320 USA
[6] Univ Chicago, Med Ctr, Chicago, IL 60637 USA
[7] Univ Piemonte Orientale, Novara, Italy
[8] Erasmus MC Canc Inst, Rotterdam, Netherlands
关键词
DEXAMETHASONE; CARFILZOMIB; CYCLOPHOSPHAMIDE; LENALIDOMIDE; MULTICENTER;
D O I
10.1038/s41408-019-0232-6
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页数:4
相关论文
共 10 条
  • [1] A Multicenter, Open-Label, Phase 1b Study of Carfilzomib, Cyclophosphamide, and Dexamethasone in Newly Diagnosed Multiple Myeloma Patients (CHAMPION-2)
    Boccia, Ralph V.
    Bessudo, Alberto
    Agajanian, Richy
    Conkling, Paul
    Harb, Wael
    Yang, Hui
    Pinchasik, Dawn
    Kimball, Amy S.
    Berenson, James R.
    [J]. CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2017, 17 (07) : 433 - 437
  • [2] Carfilzomib, cyclophosphamide, and dexamethasone in patients with newly diagnosed multiple myeloma: a multicenter, phase 2 study
    Bringhen, Sara
    Petrucci, Maria Teresa
    Larocca, Alessandra
    Conticello, Concetta
    Rossi, Davide
    Magarotto, Valeria
    Musto, Pellegrino
    Boccadifuoco, Luana
    Offidani, Massimo
    Omede, Paola
    Gentilini, Fabiana
    Ciccone, Giovannino
    Benevolo, Giulia
    Genuardi, Mariella
    Montefusco, Vittorio
    Oliva, Stefania
    Caravita, Tommaso
    Tacchetti, Paola
    Boccadoro, Mario
    Sonneveld, Pieter
    Palumbo, Antonio
    [J]. BLOOD, 2014, 124 (01) : 63 - 69
  • [3] Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies
    Cavaletti, Guido
    Jakubowiak, Andrzej J.
    [J]. LEUKEMIA & LYMPHOMA, 2010, 51 (07) : 1178 - 1187
  • [4] Myeloma: management of the newly diagnosed high-risk patient
    Dispenzieri, Angela
    [J]. HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM, 2016, : 485 - 494
  • [5] Phase II Trial of Combination of Elotuzumab, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma
    Ghobrial, Irene M.
    Badros, Ashraf Z.
    Vredenburgh, James J.
    Matous, Jeffrey
    Caola, Aaron M.
    Savell, Alexandra
    Henrick, Patrick
    Paba-Prada, Claudia E.
    Schlossman, Robert L.
    Laubach, Jacob P.
    Rosenblatt, Jacalyn
    Yee, Andrew
    Wisch, Jeffrey S.
    Farber, Charles M.
    Maegawa, Rodrigo O.
    Usmani, Saad Z.
    Cappuccio, Joseph
    Rivotto, Bradley
    Noonan, Kimberly
    Reyes, Kaitlen
    Munshi, Nikhil C.
    Anderson, Kenneth C.
    Richardson, Paul
    [J]. BLOOD, 2016, 128 (22)
  • [6] Hari P.N., 2014, Blood, V124, P3453, DOI DOI 10.1182/BLOOD.V124.21.3453.3453
  • [7] A phase 1/2 study of carfilzomib in combination with lenalidomide and low-dose dexamethasone as a frontline treatment for multiple myeloma
    Jakubowiak, Andrzej J.
    Dytfeld, Dominik
    Griffith, Kent A.
    Lebovic, Daniel
    Vesole, David H.
    Jagannath, Sundar
    Al-Zoubi, Ammar
    Anderson, Tara
    Nordgren, Brian
    Detweiler-Short, Kristen
    Stockerl-Goldstein, Keith
    Ahmed, Asra
    Jobkar, Terri
    Durecki, Diane E.
    McDonnell, Kathryn
    Mietzel, Melissa
    Couriel, Daniel
    Kaminski, Mark
    Vij, Ravi
    [J]. BLOOD, 2012, 120 (09) : 1801 - 1809
  • [8] Treatment With Carfilzomib-Lenalidomide-Dexamethasone With Lenalidomide Extension in Patients With Smoldering or Newly Diagnosed Multiple Myeloma
    Korde, Neha
    Roschewski, Mark
    Zingone, Adriana
    Kwok, Mary
    Manasanch, Elisabet E.
    Bhutani, Manisha
    Tageja, Nishant
    Kazandjian, Dickran
    Mailankody, Sham
    Wu, Peter
    Morrison, Candis
    Costello, Rene
    Zhang, Yong
    Burton, Debra
    Mulquin, Marcia
    Zuchlinski, Diamond
    Lamping, Liz
    Carpenter, Ashley
    Wall, Yvonne
    Carter, George
    Cunningham, Schuyler C.
    Gounden, Verena
    Sissung, Tristan M.
    Peer, Cody
    Maric, Irina
    Calvo, Katherine R.
    Braylan, Raul
    Yuan, Constance
    Stetler-Stevenson, Maryalice
    Arthur, Diane C.
    Kong, Katherine A.
    Weng, Li
    Faham, Malek
    Lindenberg, Liza
    Kurdziel, Karen
    Choyke, Peter
    Steinberg, Seth M.
    Figg, William
    Landgren, Ola
    [J]. JAMA ONCOLOGY, 2015, 1 (06) : 746 - 754
  • [9] Carfilzomib, pomalidomide, and dexamethasone for relapsed or refractory myeloma
    Shah, Jatin J.
    Stadtmauer, Edward A.
    Abonour, Rafat
    Cohen, Adam D.
    Bensinger, William I.
    Gasparetto, Cristina
    Kaufman, Jonathan L.
    Lentzsch, Suzanne
    Vogl, Dan T.
    Gomes, Christina L.
    Pascucci, Natalia
    Smith, David D.
    Orlowski, Robert Z.
    Durie, Brian G. M.
    [J]. BLOOD, 2015, 126 (20) : 2284 - 2290
  • [10] Design and Synthesis of an Orally Bioavailable and Selective Peptide Epoxyketone Proteasome Inhibitor (PR-047)
    Zhou, Han-Jie
    Aujay, Monette A.
    Bennett, Mark K.
    Dajee, Maya
    Demo, Susan D.
    Fang, Ying
    Ho, Mark N.
    Jiang, Jing
    Kirk, Christopher J.
    Laidig, Guy J.
    Lewis, Evan R.
    Lu, Yan
    Muchamuel, Tony
    Parlati, Francesco
    Ring, Eileen
    Shenk, Kevin D.
    Shields, Jamie
    Shwonek, Peter J.
    Stanton, Timothy
    Sun, Congcong M.
    Sylvain, Catherine
    Woo, Tina M.
    Yang, Jinfu
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2009, 52 (09) : 3028 - 3038