Synthetic wavelength based phase unwrapping in spectral domain optical coherence tomography

被引:38
作者
Hendargo, Hansford C. [1 ]
Zhao, Mingtao [1 ]
Shepherd, Neal [2 ]
Izatt, Joseph A. [1 ]
机构
[1] Duke Univ, Dept Biomed Engn, Durham, NC 27708 USA
[2] Duke Univ, George & Jean Brumley Jr Neonatal Perrinatal Res, Div Neonatol, Dept Pediat,Med Ctr, Durham, NC 27710 USA
来源
OPTICS EXPRESS | 2009年 / 17卷 / 07期
关键词
DIGITAL HOLOGRAPHY; 2-PI AMBIGUITY; MICROSCOPY; CONTRAST; REFLECTION; DYNAMICS;
D O I
10.1364/OE.17.005039
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Phase sensing implementations of spectral domain optical coherence tomography (SDOCT) have demonstrated the ability to measure nanometer-scale temporal and spatial profiles of samples. However, the phase information suffers from a 2 pi ambiguity that limits observations of larger sample displacements to lengths less than half the source center wavelength. We introduce a synthetic wavelength phase unwrapping technique in SDOCT that uses spectral windowing and corrects the 2 pi ambiguity, providing accurate measurements of sample motion with information gained from standard SDOCT processing. We demonstrate this technique by using a common path implementation of SDOCT and correctly measure phase profiles from a phantom phase object and human epithelial cheek cells which produce multiple wrapping artifacts. Using a synthetic wavelength for phase unwrapping could prove useful in Doppler or other phase based implementations of OCT. (C) 2009 Optical Society of America
引用
收藏
页码:5039 / 5051
页数:13
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