VariantAnnotation: a Bioconductor package for exploration and annotation of genetic variants

被引：213

作者：

Obenchain, Valerie ^{[1
]}

Lawrence, Michael ^{[2
]}

Carey, Vincent ^{[3
]}

Gogarten, Stephanie ^{[4
]}

Shannon, Paul ^{[1
]}

Morgan, Martin ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Program Computat Biol, Seattle, WA 98109 USA

[2] Genentech Inc, Bioinformat & Computat Biol, San Francisco, CA 94080 USA

[3] Harvard Univ, Brigham & Womens Hosp, Sch Med, Boston, MA 02115 USA

[4] Univ Washington, Dept Biostat, Seattle, WA 98195 USA

来源：

BIOINFORMATICS | 2014年 / 30卷 / 14期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/bioinformatics/btu168

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

.Summary: VariantAnnotation is an R / Bioconductor package for the exploration and annotation of genetic variants. Capabilities exist for reading, writing and filtering variant call format (VCF) files. VariantAnnotation allows ready access to additional R / Bioconductor facilities for advanced statistical analysis, data transformation, visualization and integration with diverse genomic resources.

引用

页码：2076 / 2078

页数：3

共 11 条

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