YM155, a novel small molecule survivin suppressant, exhibits curative antitumor activities in experimental human malignant lymphoma models in vivo

被引：1
作者：
Kita, A.
Nakahara, T.
Yamanaka, K.
Koutoku, H.
Takeuchi, M.
Kinoyama, I.
Matsuhisa, A.
Sasamata, M.
机构：
[1] Astellas Pharma Inc, Pharmacol Res Labs, Tsukuba, Ibaraki, Japan
[2] Astellas Pharma Inc, Mol Med Res Labs, Tsukuba, Ibaraki, Japan
[3] Astellas Pharma Inc, Chem Res Labs, Tsukuba, Ibaraki, Japan
来源：
EJC SUPPLEMENTS | 2006年 / 4卷 / 12期
关键词：
D O I：
10.1016/S1359-6349(06)70382-2
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
377
引用
收藏
页码：116 / 116
页数：1
相关论文
共 46 条
[21]   Antitumor activity of YM 155, a novel survivin suppressant, in combination with docetaxel against malignant melanoma cells. [J].
Kaneko, N. ;
Yamanaka, K. ;
Kita, A. ;
Nakata, M. ;
Koutoku, H. ;
Sasamata, M. .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (15)
[22]   Broad spectrum and potent anti tumor activity of YM155, a novel small molecule survivin suppressant, against a large scale panel of human tumor cell lines [J].
Nakahara, T. ;
Takeuchi, M. ;
Kita, A. ;
Yamanaka, K. ;
Koutoku, H. ;
Kinoyama, I. ;
Matsuhisa, A. ;
Sasamata, M. .
EJC SUPPLEMENTS, 2006, 4 (12) :122-122
[23]   Small Molecule Survivin Inhibitor YM155 Displays Potent Activity Against Human Osteosarcoma Cells [J].
Zhang, Shufeng ;
Wang, Xiaohui ;
Gu, Zhimin ;
Wang, Li .
CANCER INVESTIGATION, 2016, 34 (08) :401-407
[24]   Formulation Design and Evaluation of Liposomal Sepantronium Bromide (YM155), a Small-Molecule Survivin Suppressant, Based on Pharmacokinetic Modeling and Simulation [J].
Kohsuke Shakushiro ;
Hiroki Kawano ;
Mari Nakata ;
Aya Kita ;
Atsushi Maeda ;
Shunsuke Watanabe ;
Kazuhiro Sako ;
Naoto Oku .
Pharmaceutical Research, 2015, 32 :238-247
[25]   Formulation Design and Evaluation of Liposomal Sepantronium Bromide (YM155), a Small-Molecule Survivin Suppressant, Based on Pharmacokinetic Modeling and Simulation [J].
Shakushiro, Kohsuke ;
Kawano, Hiroki ;
Nakata, Mari ;
Kita, Aya ;
Maeda, Atsushi ;
Watanabe, Shunsuke ;
Sako, Kazuhiro ;
Oku, Naoto .
PHARMACEUTICAL RESEARCH, 2015, 32 (01) :238-247
[26]   The Mechanism of Radiosensitization by YM155, a Novel Small Molecule Inhibitor of Survivin Expression, is Associated with DNA Damage Repair [J].
Hu, Songliu ;
Fu, Songbin ;
Xu, Xiangying ;
Chen, Lin ;
Xu, Jianyu ;
Li, Bin ;
Qu, Yuanyuan ;
Yu, Hongyang ;
Lu, Shan ;
Li, Wenxin .
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2015, 37 (03) :1219-1230
[27]   Liquid chromatography-electrospray tandem mass spectrometric assay suitable for quantitation of YM155, a novel small-molecule survivin suppressant, in dog plasma [J].
Minematsu, Tsuyoshi ;
Felder, Laurie ;
Oppeneer, Todd ;
Sakazume, Masashi ;
Oikawa, Keishi ;
Hashimoto, Tadashi ;
Usui, Takashi ;
Kamimura, Hidetaka .
BIOMEDICAL CHROMATOGRAPHY, 2008, 22 (07) :763-769
[28]   YM155, a Novel Small-Molecule Survivin Suppressant, Induces Regression of Established Human Hormone-Refractory Prostate Tumor Xenografts (vol 67, pg 8014, 2007) [J].
Nakahara, Takahito ;
Kita, Aya ;
Yamanaka, Kentaro ;
Mori, Masamichi ;
Amino, Nobuaki ;
Takeuchi, Masahiro ;
Tominaga, Fumiko ;
Hatakeyama, Shinji ;
Kinoyama, Isao ;
Matsuhisa, Akira ;
Kudou, Masafumi ;
Sasamata, Masao .
CANCER RESEARCH, 2012, 72 (15) :3886-3886
[29]   A Small-Molecule Suppressant of Survivin YM155 Induces Cell Death Via Proteasomal Degradation of c-Myc in Multiple Myeloma Cells [J].
Ito, Shigeki ;
Asahi, Maki ;
Ishida, Yoji .
BLOOD, 2015, 126 (23)
[30]   Synergistic Antitumor Activities of Sepantronium Bromide (YM155), a Survivin Suppressant, in Combination with Microtubule-Targeting Agents in Triple-Negative Breast Cancer Cells [J].
Kaneko, Naoki ;
Yamanaka, Kentaro ;
Kita, Aya ;
Tabata, Kenji ;
Akabane, Takafumi ;
Mori, Masamichi .
BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2013, 36 (12) :1921-1927
12345