Evaluation of response after neoadjuvant treatment in soft tissue sarcomas; the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) recommendations for pathological examination and reporting

被引：102

作者：

Wardelmann, E. ^{[1
]}

Haas, R. L. ^{[2
]}

Bovee, J. V. M. G. ^{[3
]}

Terrier, Ph ^{[4
]}

Lazar, A. ^{[5
]}

Messiou, C. ^{[6
]}

LePechoux, C. ^{[7
]}

Hartmann, W. ^{[1
]}

Collin, F. ^{[8
]}

Fisher, C. ^{[9
]}

Mechtersheimer, G. ^{[10
]}

DeiTos, A. P. ^{[11
]}

Stacchiotti, S. ^{[12
]}

Jones, R. L. ^{[13
]}

Gronchi, A. ^{[14
]}

Bonvalot, S. ^{[15
]}

机构：

[1] Univ Hosp, Gerhard Domagk Inst Pathol, Munster, Germany

[2] Netherlands Canc Inst, Dept Radiotherapy, Plesmanlaan 121, NL-1066 CX Amsterdam, Netherlands

[3] Leiden Univ, Med Ctr, Dept Pathol, Leiden, Netherlands

[4] Gustave Roussy, Dept Med Biol & Pathol, Villejuif, France

[5] Univ Texas MD Anderson Canc Ctr, Dept Pathol, Houston, TX 77030 USA

[6] Royal Marsden Hosp, Dept Radiol, London SW3 6JJ, England

[7] Inst Gustave Roussy, Dept Radiotherapy, Paris, France

[8] Ctr Georges Francois Leclerc, Dept Pathol, Dijon, France

[9] Royal Marsden Hosp, Sarcoma Unit, London SW3 6JJ, England

[10] Heidelberg Univ, Inst Pathol, Bergheimer Str 58, D-69115 Heidelberg, Germany

[11] Gen Hosp Treviso, Dept Oncol & Anat Pathol, Treviso, Italy

[12] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy

[13] Royal Marsden Hosp, Dept Med Oncol, London SW3 6JJ, England

[14] Fdn IRCCS Ist Nazl Tumori, Dept Surg, Milan, Italy

[15] Inst Curie, Dept Surg, Paris, France

来源：

EUROPEAN JOURNAL OF CANCER | 2016年 / 53卷

关键词：

Soft tissue sarcoma; Radiotherapy; Chemotherapy; Response evaluation; Pathology; Guideline; PREOPERATIVE HYPOFRACTIONATED RADIOTHERAPY; HIGH-RISK EXTREMITY; PHASE-I TRIAL; HIGH-GRADE; HISTOLOGIC RESPONSE; HISTOPATHOLOGIC RESPONSE; PROGNOSTIC-SIGNIFICANCE; RADIATION-THERAPY; EWINGS-SARCOMA; PLUS SORAFENIB;

D O I：

10.1016/j.ejca.2015.09.021

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

At present, there is not a commonly used and generally accepted standardized approach for the pathologic evaluation of pretreated soft tissue sarcomas. Also, it is still unclear whether the cut-off for prognostic relevance is similar in the many different histological subtypes of STS. This manuscript, produced by a European Organization for Research and Treatment of Cancer - Soft Tissue and Bone Sarcoma Group (EORTC-STBSG) endorsed task force, aims to propose standardization of the pathological examination process and the reporting of STS resection specimens after neoadjuvant radio-and/or chemotherapy. (C) 2015 Elsevier Ltd. All rights reserved.

引用

页码：84 / 95

页数：12

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