ALK-positive anaplastic large T-cell lymphoma preceded by Epstein-Barr virus infection complicated by development of an aorto-esophageal fistula

被引：5

作者：

Bagshaw, SM ^{[1
]}

Crabtree, T ^{[1
]}

Green, F ^{[1
]}

Stewart, DA ^{[1
]}

机构：

[1] Univ Calgary, Dept Oncol, Calgary, AB, Canada

来源：

LEUKEMIA & LYMPHOMA | 2002年 / 43卷 / 04期

关键词：

ALK; CD30; Ki-1; anaplastic large cell lymphoma; Epstein-Barr virus; aorto-esophageal fistula;

D O I：

10.1080/10428190290017114

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report an unusual case of aggressive ALK-positive anaplastic large cell lymphoma with widespread mediastinal involvement immediately preceded by an acute Epstein-Barr virus (EBV) infection. Following initiation of chemotherapy and radiological evidence of significant tumor regression, the patient suffered a fatal massive upper gastrointestinal hemorrhage from an aorto-esophageal fistula. The relevant literature relating to EBV in the pathogenesis of ALK-lymphomas and literature relating to aorto-enteric fistula (AEF) in mediastinal lymphoma is reviewed.

引用

页码：915 / 918

页数：4

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