Tumor-induced Osteomalacia Caused by a Parotid Tumor

被引：7

作者：

Takashi, Yuichi ^{[1
]}

Kinoshita, Yuka ^{[1
]}

Ito, Nobuaki ^{[1
]}

Taguchi, Manabu ^{[1
]}

Takahashi, Masaaki ^{[2
]}

Egami, Naoya ^{[2
]}

Tajima, Shogo ^{[3
]}

Nangaku, Masaomi ^{[1
]}

Fukumoto, Seiji ^{[1
]}

机构：

[1] Tokyo Univ Hosp, Div Nephrol & Endocrinol, Bunkyo, Tokyo, Japan

[2] Tokyo Univ Hosp, Dept Otolaryngol, Bunkyo, Tokyo, Japan

[3] Tokyo Univ Hosp, Dept Pathol, Bunkyo, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2017年 / 56卷 / 05期

基金：

日本学术振兴会;

关键词：

tumor-induced osteomalacia; fibroblast growth factor 23; phosphaturic mesenchymal tumor mixed connective tissue variant; parotid gland; ONCOGENIC OSTEOMALACIA; MESENCHYMAL TUMORS; SALIVARY-GLANDS; FGF23;

D O I：

10.2169/internalmedicine.56.7565

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 77-year-old man was suspected of having tumor-induced osteomalacia (TIO) because of hypophosphatemia (1.9 mg/dL) and elevated serum fibroblast growth factor 23 (FGF23) level (186.9 pg/mL). We detected a tumor in his left parotid gland, and the FGF23 level in the left external jugular vein indicated that the tumor overproduced FGF23. After the removal of the tumor, the serum FGF23 level rapidly decreased, and the serum phosphate normalized. This is the first case of TIO caused by a tumor in a parotid gland. This case indicates that the responsible tumors for TIO can be quite diverse.

引用

页码：535 / 539

页数：5

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