The activation of B-Raf and Raf-1 after electroconvulsive shock in the rat hippocampus

被引：9
|
作者：
Kang, UG
Jeon, SH
Lee, JE
Joo, YH
Yi, JS
Park, JB
Juhnn, YS
Kim, YS [1 ]
机构：
[1] Seoul Natl Univ, Coll Med, Dept Psychiat, Seoul, South Korea
[2] Seoul Natl Univ, Coll Med, Dept Biochem, Seoul, South Korea
[3] Sungkyunkwan Univ, Sch Med, Dept Biochem & Mol Biol, Suwon, South Korea
来源：
NEUROPHARMACOLOGY | 2000年 / 39卷 / 04期
关键词：
B-Raf; Raf-1; electroconvulsive shock; hippocampus; MAPK;
D O I：
10.1016/S0028-3908(99)00184-7
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We demonstrated that ECS activates the kinase activity of B-Raf and Raf-l in the rat hippocampus. The activity was maximal at one minute after ECS and temporally coincided with the increased membrane translocation of Rafs and the reported activity of MAPK, but not with the phosphorylation of Rafs. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：703 / 706
页数：4
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