Pd-catalyzed alkyl to aryl migration and cyclization: An efficient synthesis of fused polycycles via multiple C-H activation

被引：228

作者：

Huang, QH ^{[1
]}

Fazio, A ^{[1
]}

Dai, GX ^{[1
]}

Campo, MA ^{[1
]}

Larock, RC ^{[1
]}

机构：

[1] Iowa State Univ, Dept Chem, Ames, IA 50011 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2004年 / 126卷 / 24期

关键词：

D O I：

10.1021/ja047980y

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel palladium migration methodology for the synthesis of complex fused polycycles has been developed. This process involves 1,4-palladium alkyl to aryl migrations via through-space C-H activation, followed by intramolecular arylation or an intermolecular Heck reaction providing a very efficient way to synthesize fused ring systems. Copyright © 2004 American Chemical Society.

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页码：7460 / 7461

页数：2

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