Fabrication of multiphasic and regio-specifically functionalized PRINT® particles of controlled size and shape

被引：50

作者：

Zhang, H. ^{[1
]}

Nunes, J. K. ^{[1
]}

Gratton, S. E. A. ^{[1
]}

Herlihy, K. P. ^{[1
]}

Pohlhaus, P. D. ^{[2
]}

DeSimone, J. M. ^{[1
,3
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

[2] Liquidia Technol, Res Triangle Pk, NC 27709 USA

[3] N Carolina State Univ, Dept Chem & Biomol Engn, Raleigh, NC 27695 USA

来源：

NEW JOURNAL OF PHYSICS | 2009年 / 11卷

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

JANUS PARTICLES; MONODISPERSE; REPLICATION; ANISOTROPY; DESIGN;

D O I：

10.1088/1367-2630/11/7/075018

中图分类号：

O4 [物理学];

学科分类号：

0702 ;

摘要：

Using Particle Replication In Nonwetting Templates (PRINT(R)) technology, multiphasic and regio-specifically functionalized shape-controlled particles have been fabricated that include end-labeled particles via post-functionalization; biphasic Janus particles that integrate two compositionally different chemistries into a single particle; and more complex multiphasic shape-specific particles. Controlling the anisotropic distribution of matter within a particle creates an extra parameter in the colloidal particle design, providing opportunities to generate advanced particles with versatile and tunable compositions, properties, and thus functionalities. Owing to their robust characteristics, these multiphasic and regio-specifically functionalized PRINT particles should be promising platforms for applications in life science and materials science.

引用

页数：16

共 38 条

[1] Encoding microcarriers: Present and future technologies [J].