Analytical applications of planar bilayer lipid membranes

被引：19
|
作者：
Trojanowicz, M
Mulchandani, A
机构：
[1] Univ Warsaw, Dept Chem, PL-02093 Warsaw, Poland
[2] Inst Nucl Chem & Technol, PL-03195 Warsaw, Poland
[3] Univ Calif Riverside, Dept Environm Chem & Engn, Riverside, CA 92521 USA
来源：
ANALYTICAL AND BIOANALYTICAL CHEMISTRY | 2004年 / 379卷 / 03期
关键词：
D O I：
10.1007/s00216-004-2611-4
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The methods of preparation of planar bilayer lipid membrane (BLM) and its applications are discussed. BLM are held together by non-covalent hydrophobic interactions of amphiphilic lipids with hydrophilic and lipophilic parts, forming a two-dimensional fluid structure for other membrane constituents. A free-suspended planar BLM between two aqueous phases can be formed across a small window made in a hydrophobic septum, by spreading a lipid solution with a thin brush. The analytical applications of planar BLM can be employed in the design of a variety of chemical and biochemical sensors.
引用
收藏
页码：347 / 350
页数：4
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