Asperpyrone F, a new dimeric naphtho-γ-pyrone from the edible fungus Pleurotus ostreatus

被引:16
作者
Cai, Xu [1 ,2 ]
Yu, Yang [3 ]
Li, Qian [2 ]
Chen, Ben-Ke [2 ]
Huang, Yun [2 ]
Zou, Xian-Wei [2 ]
Tang, Jin-Tian [2 ]
Huang, Bi-Sheng [1 ]
机构
[1] Hubei Univ Chinese Med, Key Lab Minist Educ Tradit Chinese Med Resource &, Wuhan, Hubei, Peoples R China
[2] Tsinghua Univ, Dept Engn Phys, Key Lab Particle & Radiat Imaging, Minist Educ, Beijing, Peoples R China
[3] Shandong Univ Tradit Chinese Med, Coll Pharm, Jinan, Shandong, Peoples R China
基金
中国博士后科学基金; 中国国家自然科学基金;
关键词
Pleurotus ostreatus; bis-naphtho-gamma-pyrone; antioxidant activity; immunomodulatory activity; CULINARY-MEDICINAL MUSHROOM; SESQUITERPENOIDS; POLYSACCHARIDES; FERMENTATION; METABOLITES; ANTITUMOR; MYCELIA;
D O I
10.1080/14786419.2018.1481844
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A new dimeric naphtho-gamma-pyrone, asperpyrone F (1), along with six known ones, asperpyrones B (2) and C (3), fonsecinones A (4) and B (5), aurasperones A (6) and E (7), have been isolated from the solid culture of the edible fungus Pleurotus ostreatus. The structures of 1-7 were determined mainly by NMR and MS experiments. The absolute configuration of compound 1 was assigned via the circular dichroism (CD) data analysis. Compounds 1-7 showed modest antioxidant and immunomodulatory activities. All compounds were isolated from the fungus P. ostreatus for the first time. [GRAPHICS] .
引用
收藏
页码:1953 / 1960
页数:8
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