Anticancer drug discovery from Chinese medicinal herbs

被引：80

作者：

Huang, Mu-Yang ^{[1
]}

Zhang, Le-Le ^{[1
]}

Ding, Jian ^{[2
]}

Lu, Jin-Jian ^{[1
]}

机构：

[1] Univ Macau, Inst Chinese Med Sci, State Key Lab Qual Res Chinese Med, 7014,N22 Ave Univ, Taipa, Macao, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Div Antitumor Pharmacol, Shanghai, Peoples R China

来源：

CHINESE MEDICINE | 2018年 / 13卷

关键词：

Chinese medicinal herbs; Anticancer; Drug discovery; Natural products; Formulae; DOXORUBICIN-INDUCED CARDIOTOXICITY; CANCER STATISTICS; NATURAL-PRODUCTS; STRUCTURAL MODIFICATION; CHEMICAL-CONSTITUENTS; SIGNALING PATHWAY; THERAPY; APOPTOSIS; FORMULA; COMBINATION;

D O I：

10.1186/s13020-018-0192-y

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Cancer is still presenting a serious threat to human health worldwide. The understanding of the complex biology of cancer and the development of oncotherapy have led to increasing treatment approaches such as targeted therapy and immunotherapy. Chinese medicinal herbs have attracted considerable attention due to their potential anticancer effects. Some natural products or formulae from Chinese medicinal herbs with directly or indirectly anticancer effects have been reported. In this article, we summarized the current progression on development of anticancer drugs from Chinese medicinal herbs, toward providing ideas for further development and application of Chinese medicinal herbs in cancer therapy.

引用

页数：9

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