Cognitive Impairment Is a Common Comorbidity in Deceased COVID-19 Patients: A Hospital-Based Retrospective Cohort Study

被引：29

作者：

Martin-Jimenez, Paloma ^{[1
]}

Munoz-Garcia, Mariana, I ^{[1
]}

Seoane, David ^{[1
]}

Roca-Rodriguez, Lucas ^{[1
]}

Garcia-Reyne, Ana ^{[2
]}

Lalueza, Antonio ^{[2
,3
,5
]}

Maestro, Guillermo ^{[2
]}

Folgueira, Dolores ^{[3
,4
]}

Blanco-Palmero, Victor A. ^{[1
,5
,6
]}

Herrero-San Martin, Alejandro ^{[1
,5
,6
]}

Llamas-Velasco, Sara ^{[1
,5
,6
]}

Perez-Martinez, David A. ^{[1
,3
,5
,6
]}

Gonzalez-Sanchez, Marta ^{[1
,5
,6
]}

Villarejo-Galende, Alberto ^{[1
,3
,5
,6
]}

机构：

[1] Hosp Univ 12 Octubre, Dept Neurol, Madrid, Spain

[2] Hosp Univ 12 Octubre, Dept Internal Med, Madrid, Spain

[3] Univ Complutense Madrid, Sch Med, Dept Med, Madrid, Spain

[4] Hosp Univ 12 Octubre, Dept Microbiol, Madrid, Spain

[5] Inst Invest Hosp 12 Octubre I 12, Grp Neurodegenerat Dis, Madrid, Spain

[6] Biomed Res Networking Ctr Neurodegenerat Dis CIBE, Madrid, Spain

来源：

JOURNAL OF ALZHEIMERS DISEASE | 2020年 / 78卷 / 04期

关键词：

Cognitive impairment; COVID-19; dementia; morbidity; mortality; CORONAVIRUS DISEASE 2019; DEMENTIA; MORTALITY; CARE;

D O I：

10.3233/JAD-200937

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We analyzed the frequency of cognitive impairment (CI) in deceased COVID-19 patients at a tertiary hospital in Spain. Among the 477 adult cases who died after admission from March 1 to March 31, 2020, 281 had confirmed COVID-19. CI (21.1% dementia and 8.9% mild cognitive impairment) was a common comorbidity. Subjects with CI were older, tended to live in nursing homes, had shorter time from symptom onset to death, and were rarely admitted to the ICU, receiving palliative care more often. CI is a frequent comorbidity in deceased COVID-19 subjects and is associated with differences in care.

引用

页码：1367 / 1372

页数：6

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