Nanoscale ZnO-enhanced fluorescence detection of protein interactions

被引：164

作者：

Dorfman, Adam ^{[1
]}

Kumar, Nitin ^{[1
]}

Hahm, Jong-in ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem Engn, University Pk, PA 16802 USA

来源：

ADVANCED MATERIALS | 2006年 / 18卷 / 20期

关键词：

D O I：

10.1002/adma.200502616

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enhanced fluorescence emission is detected from interacting protein pairs of dichlorotriazinylaminofluoresceinstreptavidin and biotinylated bovine serum albumin (see figure) that are adsorbed onto periodically spaced, square-patterned ZnO nanostructures. This florescence-enhancement capability of nanoscale ZnO and its potential easy integration into biosensor arrays may allow ultrasensitive protein detection, which is needed in the areas of biomedical research and in large-scale testing and screening.

引用

页码：2685 / +

页数：7

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