Nanoscale ZnO-enhanced fluorescence detection of protein interactions

被引：163
|
作者：
Dorfman, Adam [1 ]
Kumar, Nitin [1 ]
Hahm, Jong-in [1 ]
机构：
[1] Penn State Univ, Dept Chem Engn, University Pk, PA 16802 USA
来源：
ADVANCED MATERIALS | 2006年 / 18卷 / 20期
关键词：
D O I：
10.1002/adma.200502616
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Enhanced fluorescence emission is detected from interacting protein pairs of dichlorotriazinylaminofluoresceinstreptavidin and biotinylated bovine serum albumin (see figure) that are adsorbed onto periodically spaced, square-patterned ZnO nanostructures. This florescence-enhancement capability of nanoscale ZnO and its potential easy integration into biosensor arrays may allow ultrasensitive protein detection, which is needed in the areas of biomedical research and in large-scale testing and screening.
引用
收藏
页码：2685 / +
页数：7
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