Cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program

被引：23

作者：

Rim, Sun Hee ^{[1
]}

Allaire, Benjamin T. ^{[2
]}

Ekwueme, Donatus U. ^{[1
]}

Miller, Jacqueline W. ^{[1
]}

Subramanian, Sujha ^{[2
]}

Hall, Ingrid J. ^{[1
]}

Hoerger, Thomas J. ^{[2
]}

机构：

[1] Ctr Dis Control & Prevent, Div Canc Prevent & Control, 4770 Buford Highway,NE,MS S107-4, Atlanta, GA 30341 USA

[2] RTI Int, Res Triangle Pk, NC USA

来源：

CANCER CAUSES & CONTROL | 2019年 / 30卷 / 08期

关键词：

Breast cancer; Screening; Cost-effectiveness; Economic analysis; NBCCEDP; UNDERSERVED WOMEN; CARE; DIAGNOSIS; MAMMOGRAPHY; STAGE; ASSOCIATION; INSURANCE; MODEL;

D O I：

10.1007/s10552-019-01178-y

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

PurposeTo estimate the cost-effectiveness of breast cancer screening in the National Breast and Cervical Cancer Early Detection Program (NBCCEDP).MethodsUsing a modified CISNET breast cancer simulation model, we estimated outcomes for women aged 40-64years associated with three scenarios: breast cancer screening within the NBCCEDP, screening in the absence of the NBCCEDP (no program), and no screening through any program. We report screening outcomes, cost, quality-adjusted life-years (QALYs), incremental cost-effectiveness ratios (ICERs), and sensitivity analyses results.ResultsCompared with no program and no screening, the NBCCEDP lowers breast cancer mortality and improves QALYs, but raises health care costs. Base-case ICER for the program was $51,754/QALY versus no program and $50,223/QALY versus no screening. Probabilistic sensitivity analysis ICER for the program was $56,615/QALY [95% CI $24,069, $134,230/QALY] versus no program and $51,096/QALY gained [95% CI $26,423, $97,315/QALY] versus no screening.ConclusionsOn average, breast cancer screening in the NBCCEDP was cost-effective compared with no program or no screening.

引用

页码：819 / 826

页数：8

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