The Fraction of Cancer Attributable to Ways of Life, Infections, Occupation, and Environmental Agents in Brazil in 2020

被引：67

作者：

Azevedo e Silva, Gulnar ^{[1
]}

de Moura, Lenildo ^{[2
]}

Curado, Maria Paula ^{[3
,4
]}

Gomes, Fabio da Silva ^{[5
]}

Otero, Ubirani ^{[5
]}

Machado de Rezende, Leandro Fornias ^{[6
]}

Daumas, Regina Paiva ^{[7
]}

Guimaraes, Raphael Mendonca ^{[8
]}

Meira, Karina Cardoso ^{[9
]}

Leite, Iuri da Costa ^{[7
]}

Valente, Joaquim Goncalves ^{[7
]}

Moreira, Ronaldo Ismerio ^{[10
]}

Koifman, Rosalina ^{[6
]}

Malta, Deborah Carvalho ^{[11
]}

de Campos Mello, Marcia Sarpa ^{[5
]}

Guimaraes Guedes, Thiago Wagnos ^{[1
]}

Boffetta, Paolo ^{[12
]}

机构：

[1] Univ Estado Rio De Janeiro, Inst Social Med, Rio De Janeiro, Rio De Janeiro, Brazil

[2] Pan Amer Hlth Org, Brasilia, DF, Brazil

[3] Hosp AC Camargo Fund Antonio Prudente, AC Camargo Canc Ctr, Sao Paulo, SP, Brazil

[4] Int Prevent Res Inst, Lyon, France

[5] Minist Hlth, Natl Canc Inst, Rio De Janeiro, Rio De Janeiro, Brazil

[6] Univ Sao Paulo, Sch Med, Dept Prevent Med, Sao Paulo, SP, Brazil

[7] Minist Hlth, Natl Sch Publ Hlth, Oswaldo Cruz Fdn, Rio De Janeiro, Rio De Janeiro, Brazil

[8] Minist Hlth, Joaquim Venancio Polytech Sch Hlth, Oswaldo Cruz Fdn, Rio De Janeiro, Rio De Janeiro, Brazil

[9] Univ Fed Rio Grande do Norte, Sch Nursing, BR-59072970 Natal, RN, Brazil

[10] Minist Hlth, Oswaldo Cruz Fdn, Natl Inst Infectolgy, Rio De Janeiro, Rio De Janeiro, Brazil

[11] Minist Hlth, Hlth Surveillance Secretariat, Brasilia, DF, Brazil

[12] Icahn Sch Med Mt Sinai, Tisch Canc Inst, New York, NY 10029 USA

来源：

PLOS ONE | 2016年 / 11卷 / 02期

关键词：

PHYSICAL-ACTIVITY; LUNG-CANCER; RISK; BURDEN; HEALTH; PREVALENCE; BEHAVIORS; EXPOSURE; SMOKING; STATE;

D O I：

10.1371/journal.pone.0148761

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Many human cancers develop as a result of exposure to risk factors related to the environment and ways of life. The aim of this study was to estimate attributable fractions of 25 types of cancers resulting from exposure to modifiable risk factors in Brazil. The prevalence of exposure to selected risk factors among adults was obtained from population-based surveys conducted from 2000 to 2008. Risk estimates were based on data drawn from meta-analyses or large, high quality studies. Population-attributable fractions (PAF) for a combination of risk factors, as well as the number of preventable deaths and cancer cases, were calculated for 2020. The known preventable risk factors studied will account for 34% of cancer cases among men and 35% among women in 2020, and for 46% and 39% deaths, respectively. The highest attributable fractions were estimated for tobacco smoking, infections, low consumption of fruits and vegetables, excess weight, reproductive factors, and physical inactivity. This is the first study to systematically estimate the fraction of cancer attributable to potentially modifiable risk factors in Brazil. Strategies for primary prevention of tobacco smoking and control of infection and the promotion of a healthy diet and physical activity should be the main priorities in policies for cancer prevention in the country.

引用

页数：13

共 61 条

[21]

Figueira-Silva Cecília M., 2004, Rev. Soc. Bras. Med. Trop., V37, P409

[22]

Girianelli VR, 2011, REV BRAS GINECOL OBS, V32, P39

[23] The human papillomavirus infection in men study: Human papillomavirus prevalence and type distribution among men residing in Brazil, Mexico, and the United States [J].

Giuliano, Anna R. ;

Lazcano-Ponce, Eduardo ;

Villa, Luisa L. ;

Flores, Roberto ;

Salmeron, Jorge ;

Lee, Ji-Hyun ;

Papenfuss, Mary R. ;

Abrahamsen, Martha ;

Jolles, Emily ;

Nielson, Carrie M. ;

Baggio, Maria Luisa ;

Silva, Roberto ;

Quiterio, Manuel .

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, 2008, 17 (08) :2036-2043

[24]

Gomes F. S., 2011, SCN News, P57

[25]

Hamra GB, 2014, ENVIRON HEALTH PERSP, V122, P906, DOI [10.1289/ehp.1408092, 10.1289/ehp/1408092]

[26] The hallmarks of cancer [J].

Hanahan, D ;

Weinberg, RA .

CELL, 2000, 100 (01) :57-70

[27]

*IARC, 1997, HDB CANC PREV, V1

[28]

IBGE, 2008, PESQ NAC AM DOM

[29] Attributable causes of cancer in Japan in 2005-systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan [J].

Inoue, M. ;

Sawada, N. ;

Matsuda, T. ;

Iwasaki, M. ;

Sasazuki, S. ;

Shimazu, T. ;

Shibuya, K. ;

Tsugane, S. .

ANNALS OF ONCOLOGY, 2012, 23 (05) :1362-1369

[30]

[Instituto Nacional de Cancer Brasil. Ministerio da Saude], 2014, EST CANC REG CANC BA

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