Preparation, structural and microstructural characterization of Ti-30Nb-10Ta-5Zr alloy for biomedical applications

被引:22
作者
Gudkov, Sergey V. [1 ]
Simakin, Alexander V. [1 ]
Konushkin, Sergey V. [2 ]
Ivannikov, Alexander Yu [2 ]
Nasakina, Elena O. [2 ]
Shatova, Lyudmila A. [3 ]
Kolmakov, Alexey G. [2 ]
Sevostyanov, Mikhail A. [2 ,4 ]
机构
[1] Russian Acad Sci, Prokhorov Gen Phys Inst, 38 Vavilova St, Moscow 119991, Russia
[2] Russian Acad Sci, AA Baikov Inst Met & Mat Sci, Moscow, Russia
[3] Voronezh State Tech Univ, Voronezh, Russia
[4] All Russian Res Inst Phytopatol, Vyazemskii, Moscow Oblast, Russia
来源
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T | 2020年 / 9卷 / 06期
关键词
Titanium; Tantalum; Niobium; Zirconium; Biocompatibility; Mechanical properties; MECHANICAL-PROPERTIES; TITANIUM-ALLOY; SHAPE-MEMORY; DEFORMATION-BEHAVIOR; OXIDATIVE STRESS; TI; NB; BETA; TA; STRENGTH;
D O I
10.1016/j.jmr.2020.11.036
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Ti-30Nb-10Ta-5Zr alloy was produced and studied in the work. Plates and wires were made of this alloy. The alloy was shown to have pure beta-crystalline phase and to possess the required mechanical properties. Microstructures with a height of the order of several hundred nm, located at a distance of 1.5-2.0 mu m were observed on the surface of the alloy. From the point of view of reactive oxygen species generation and long-lived reactive protein species formation, the Ti-30Nb-10Ta-5Zr alloy is more preferrable than nitinol. Cultivation of cell cultures on Ti-30Nb-10Ta-5Zr surfaces resulted in high mitotic index (2%) and low content of non-viable cells (<5%). The cells were actively attaching and spreading on the alloy. Biocompatibility of Ti-30Nb-10Ta-5Zr was confirmed by the experiments on implantation of the alloy as plates and coiled wires. The surface morphology of the specimens did not alter significantly after the biological trials. It can be suggested that Ti-30Nb-10Ta-5Zr alloy is an appropriate material for potential medical applications. (C) 2020 The Author(s). Published by Elsevier B.V.
引用
收藏
页码:16018 / 16028
页数:11
相关论文
共 68 条
[1]   Study of the influence of Zr on the mechanical properties and functional response of Ti-Nb-Ta-Zr-O alloy for orthopedic applications [J].
Acharya, Srijan ;
Panicker, Arpana Gopi ;
Laxmi, Devara Vijaya ;
Suwas, Satyam ;
Chatterjee, Kaushik .
MATERIALS & DESIGN, 2019, 164
[2]  
Akil Samuel, 2018, J Clin Orthop Trauma, V9, P3, DOI 10.1016/j.jcot.2017.10.003
[3]   Effect of alkaline treatment of pure titanium and its alloys on the bonding strength of dental veneering resins [J].
Ban, S .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2003, 66A (01) :138-145
[4]   Laser-assisted nanostructuring of Tungsten in liquid environment [J].
Barmina, E. V. ;
Stratakis, E. ;
Barberoglou, M. ;
Stolyarov, V. N. ;
Stolyarov, I. N. ;
Fotakis, C. ;
Shafeev, G. A. .
APPLIED SURFACE SCIENCE, 2012, 258 (15) :5898-5902
[5]   A new look at biomedical Ti-based shape memory alloys [J].
Biesiekierski, Arne ;
Wang, James ;
Gepreel, Mohamed Abdel-Hady ;
Wen, Cuie .
ACTA BIOMATERIALIA, 2012, 8 (05) :1661-1669
[6]   Prolongation of oxidative stress by long-lived reactive protein species induced by X-ray radiation and their genotoxic action [J].
Bruskov, Vadim I. ;
Karp, Olga E. ;
Garmash, Svetlana A. ;
Shtarkman, Ilya N. ;
Chernikov, Anatoly V. ;
Gudkov, Sergey V. .
FREE RADICAL RESEARCH, 2012, 46 (10) :1280-1290
[7]   Effects of Nb on Superelasticity and Low Modulus Properties of Metastable β-Type Ti-Nb-Ta-Zr Biomedical Alloys [J].
Chen, Juan ;
Ma, Fengcang ;
Liu, Ping ;
Wang, Chaohu ;
Liu, Xinkuan ;
Li, Wei ;
Han, Qingyou .
JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE, 2019, 28 (03) :1410-1418
[8]  
Chernikov AV, 2007, BIOFIZIKA+, V52, P244
[9]   Exogenous 8-Oxo-7,8-dihydro-2′-deoxyguanosine: Biomedical Properties, Mechanisms of Action, and Therapeutic Potential [J].
Chernikov, A. V. ;
Gudkov, S. V. ;
Usacheva, A. M. ;
Bruskov, V. I. .
BIOCHEMISTRY-MOSCOW, 2017, 82 (13) :1686-1701
[10]   POTENTIAL APPLICATIONS OF CERTAIN NICKEL-TITANIUM (NITINOL) ALLOYS [J].
CIVJAN, S ;
HUGET, EF ;
DESIMON, LB .
JOURNAL OF DENTAL RESEARCH, 1975, 54 (01) :89-96