Severe Strongyloidiasis in Solid Organ Transplant Recipients: Should We Preventively Treat the Recipient, the Donor, or Both?

被引：6

作者：

Eperon, Gilles ^{[1
,2
,3
,7
,8
,9
]}

Tourret, Jerome ^{[1
,4
,7
,9
,10
]}

Ailioaie, Oana ^{[1
,4
,7
,10
]}

Paris, Luc ^{[1
,5
,7
,9
,11
]}

Mercadal, Lucile ^{[4
,7
,10
]}

Mayaux, Julien ^{[1
,6
,7
,12
]}

Caumes, Eric ^{[1
,2
]}

Barrou, Benoit ^{[1
,4
,7
,9
,10
]}

机构：

[1] Univ Paris 06, Paris, France

[2] Hop Pitie Salpetriere Charles Foix, AP HP, Serv Malad Infect & Trop, Paris, France

[3] HUG, Dept Med Communautaire Premier Recours & Urgences, Serv Med Trop & Humanitaire, Rue Gabrielle Perret Gentil 4, CH-1211 Geneva 14, Switzerland

[4] Hop Pitie Salpetriere Charles Foix, AP HP, Dept Urol Nephrol & Transplantat, Paris, France

[5] Hop Pitie Salpetriere Charles Foix, AP HP, Lab Parasitol Mycol, Paris, France

[6] Hop Pitie Salpetriere Charles Foix, AP HP, Serv Pneumol & Reanimat Med, Paris, France

[7] AP HP, Paris, France

[8] Hop La Pitie Salpetriere, Serv Malad Infect Trop, Paris, France

[9] UPMC, Fac Med, Dept Med, Paris, France

[10] Hop La Pitie Salpetriere, Dept Urol Nephrol & Transplantat, Paris, France

[11] Hop La Pitie Salpetriere, Lab Parasitol & Mycol, Paris, France

[12] Hop La Pitie Salpetriere, Serv Reanimat Med, Paris, France

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 2018年 / 98卷 / 04期

关键词：

HYPERINFECTION SYNDROME; STERCORALIS INFECTION; IMMIGRANTS; IVERMECTIN; TRAVELERS;

D O I：

10.4269/ajtmh.17-0234

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Strongyloidiasis is caused by a soil-transmitted helminth that is endemic in tropical and subtropical countries. The parasite can complete its life cycle without leaving the host, allowing autoinfection and persistence. The risk of infection in travelers is low, but the disease may become lethal following immunosuppression. In case of solid organ transplantation, the risk of donor transmission has been suspected for several years. However, the management of live donors in this context has only recently been considered, and no guidelines exist for the management of deceased donors. To highlight the complexity of diagnosing, treating, and preventing strongyloidiasis donor transmission, we describe a case of possible transmission of severe strongyloidiasis to a kidney transplant recipient with limited travel history. Taking into account the difficulty of diagnosing chronic strongyloidiasis infection and the increase in travel and immunosuppressive treatments, we recommend pragmatic management guidelines to limit the risks of infection.

引用

页码：941 / 944

页数：4

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