New Biocompatible Microgels

被引：16

作者：

Imaz, Ainara ^{[1
]}

Forcada, Jacqueline ^{[1
]}

机构：

[1] Univ Basque Country, Fac Ciencias Quim, Grp Ingn Quim, San Sebastian 20080, Spain

来源：

MACROMOLECULAR SYMPOSIA | 2009年 / 281卷

关键词：

emulsion polymerization; microgels; stimuli-sensitive polymers; DRUG-DELIVERY; POLY(N-VINYLCAPROLACTAM); HYDROGELS; WATER;

D O I：

10.1002/masy.200950711

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Microgel particles have received an increasing interest in the biomedical field. Temperature-sensitive microgels gained particular interest due to their potential use as controlled drug delivery systems. With the objective to produce new thermoresponsive biocompatible microgels, the synthesis and characterization of two families of microgel particles obtained by using N-vinylcaprolactam (VCL) as main monomer and N,N'-methylenbisacrylamide (BA) or poly(ethylene glycol) diacrylate (PEGDA) as crosslinkers are described. Evidence of hydrolysis VCL during polymerization is also presented.

引用

页码：85 / 88

页数：4

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