A Quantitative Universal Detection System for Organic Compounds in Gas Chromatography with Isotopically Enriched 13CO2

被引：17

作者：

Cueto Diaz, Sergio ^{[1
]}

Ruiz Encinar, Jorge ^{[1
]}

Sanz-Medel, Alfredo ^{[1
]}

Garcia Alonso, J. Ignacio ^{[1
]}

机构：

[1] Univ Oviedo, Dept Phys & Analyt Chem, E-33006 Oviedo, Spain

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2009年 / 48卷 / 14期

关键词：

analytical methods; gas chromatography; isotopic labeling; mass spectrometry; quantification; DILUTION MASS-SPECTROMETRY; PROTEIN-PHOSPHORYLATION; QUANTIFICATION; PERFORMANCE; STANDARD;

D O I：

10.1002/anie.200805545

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Cheap and cheerful: Postcolumn carbon-isotope dilution with 13CO2 in combination with the coupling of gas chromatography, combustion, and EIMS (valve in position B in the picture) provides a generic quantitative approach for every organic compound without the need for specific standards. A GC-MS instrument can be upgraded by a simple low-cost modification without any loss of the structural information provided by electron ionization sources. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2561 / 2564

页数：4

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