Higher vitamin D status and supplementation may be associated with risks

被引：13

作者：

Korgavkar, Kaveri ^{[1
,2
]}

Xiong, Michael ^{[1
,2
]}

Weinstock, Martin A. ^{[1
,2
,3
,4
]}

机构：

[1] Vet Adm Med Ctr, Dermatoepidemiol Unit, Providence, RI 02908 USA

[2] Brown Univ, Alpert Med Sch, Dept Dermatol, Providence, RI 02912 USA

[3] Brown Univ, Alpert Med Sch, Dept Epidemiol, Providence, RI 02912 USA

[4] Rhode Isl Hosp, Dept Dermatol, Providence, RI USA

来源：

EUROPEAN JOURNAL OF DERMATOLOGY | 2014年 / 24卷 / 04期

关键词：

epidemiology; vitamin D; SERUM 25-HYDROXYVITAMIN D; RANDOMIZED CONTROLLED-TRIAL; PANCREATIC-CANCER RISK; ISCHEMIC-HEART-DISEASE; MELANOMA SKIN-CANCER; BASAL-CELL CARCINOMA; ALL-CAUSE MORTALITY; PROSTATE-CANCER; MYOCARDIAL-INFARCTION; PROSPECTIVE COHORT;

D O I：

10.1684/ejd.2014.2318

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The prevalence of low vitamin D levels and associated risks has led to an increase in supplementation. However, a ''U-shaped'' relationship has been suggested between vitamin D status and adverse effects, with risks observed both in low and high levels. While risks associated with low levels of vitamin D have been extensively studied, the risks of higher levels of vitamin D have not been as widely circulated. We sought to describe key observed adverse risks with vitamin D supplementation and higher serum 25(OH)-D levels in healthy adult populations.

引用

页码：428 / 434

页数：7

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