The emerging role of induced hypothermia in the management of acute stroke

被引：25

作者：

Feigin, VL

Anderson, CS

Rodgers, A

Anderson, NE

Gunn, AJ

机构：

[1] Univ Auckland, Clin Trials Res Unit, Auckland 1, New Zealand

[2] Univ Auckland, Dept Med, Auckland 1, New Zealand

[3] Univ Auckland, Dept Paediat, Res Ctr Dev Med & Biol, Auckland 1, New Zealand

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2002年 / 9卷 / 05期

关键词：

stroke; induced hypothermia; trials; ischaemic stroke; haemorrhagic stroke; management; review;

D O I：

10.1054/jocn.2001.1072

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Current treatment of acute stroke remains unsatisfactory. This review presents experimental and clinical data which suggest that mild induced hypothermia could be a potent and practicable neuroprotective treatment of acute ischaemic stroke and intracerebral haemorrhage. Hypothermia, if proven to be safe, effective and widely practicable in patients with acute stroke, could have an enormous positive impact on reducing the burden of stroke worldwide. Critical issues that will need to be considered in a well designed randomised controlled trial of induced hypothermia in acute stroke patients are discussed. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：502 / 507

页数：6

共 107 条

[1] Hyperthermia delayed by 24 hours aggravates neuronal damage in rat hippocampus following global ischemia [J].