Synthesis, Characterization and Biological Activity of Schiff Bases

被引：0

作者：

Ashraf, Muhammad Aqeel ^{[1
]}

Mahmood, Karamat ^{[1
]}

Wajid, Abdul ^{[1
]}

Maah, Mohd Jamil ^{[2
,3
]}

Yusoff, Ismail ^{[2
,3
]}

机构：

[1] Islamia Univ Bahawalpur, Fac Sci, Dept Chem, Bahawalpur 63100, Pakistan

[2] Univ Malaya, Dept Chem, Fac Sci, Kuala Lumpur 50603, Malaysia

[3] Univ Malaya, Dept Geol, Fac Sci, Kuala Lumpur 50603, Malaysia

来源：

CHEMISTRY AND CHEMICAL PROCESS | 2011年

关键词：

schiff bases; benzthiozol; aminophenol; antibacterial; antifungal; COMPLEXES; DERIVATIVES; EQUILIBRIA; CORROSION; COPPER; SALICYLALDEHYDE; AMINOPYRIDINES; TAUTOMERISM; CYCLOHEXENE; OXIDATION;

D O I：

暂无

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Three new series of biologically active amino substituted Schiff bases with general formula, R1N=CHR2. Here R1 = 2-amino-benzthiazole, 4-amino-salicylic acid and 4-aminophenol. R2 =4-chloro-benzaldehyde, 2-chloro-benzaldehyde, salicylaldehyde, vanillin and benzaldehyde were synthesized by the reaction of three different amino substituted compounds and substituted aldehydes in ethanol. Such compounds were characterized by different physico-chemical techniques like, melting point, elemental analysis, multinuclear NMR (1H, 13C). The free ligands and their metal complexes have been screened for their in vitro biological activities against bacteria, fungi and yeast. The metal complexes show more potent activities compared with Schiff base ligands.

引用

页码：1 / 7

页数：7

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