Antiartherosclerotic Effects of Plant Flavonoids

被引：168

作者：

Salvamani, Shamala ^{[1
]}

Gunasekaran, Baskaran ^{[1
]}

Shaharuddin, Noor Azmi ^{[1
]}

Ahmad, Siti Aqlima ^{[1
]}

Shukor, Mohd Yunus ^{[1
]}

机构：

[1] Univ Putra Malaysia, Fac Biotechnol & Biomol Sci, Dept Biochem, Serdang 43400, Selangor, Malaysia

来源：

BIOMED RESEARCH INTERNATIONAL | 2014年 / 2014卷

关键词：

LOW-DENSITY-LIPOPROTEIN; COENZYME-A REDUCTASE; ANTIOXIDANT PROPERTIES; GREEN TEA; HIBISCUS-SABDARIFFA; IN-VITRO; CHOLESTEROL ACYLTRANSFERASE; ADIPOCYTE DIFFERENTIATION; ENDOTHELIAL DYSFUNCTION; HYPERICUM-PERFORATUM;

D O I：

10.1155/2014/480258

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Atherosclerosis is the process of hardening and narrowing the arteries. Atherosclerosis is generally associated with cardiovascular diseases such as strokes, heart attacks, and peripheral vascular diseases. Since the usage of the synthetic drug, statins, leads to various side effects, the plants flavonoids with antiartherosclerotic activity gained much attention and were proven to reduce the risk of atherosclerosis in vitro and in vivo based on different animal models. The flavonoids compounds also exhibit lipid lowering effects and anti-inflammatory and antiatherogenic properties. The future development of flavonoids-based drugs is believed to provide significant effects on atherosclerosis and its related diseases. This paper discusses the antiatherosclerotic effects of selected plant flavonoids such as quercetin, kaempferol, myricetin, rutin, naringenin, catechin, fisetin, and gossypetin.

引用

页数：11

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