Non-operative management of rectal cancer

被引：6
作者：
Greer, Jonathan B. [1 ]
Hawkins, Alexander T. [2 ]
机构：
[1] Johns Hopkins Univ, Sch Med, Dept Surg, Div Surg Oncol, Baltimore, MD 21205 USA
[2] Vanderbilt Univ, Med Ctr, Dept Surg, Sect Colon & Rectal Surg, 1161 21st Ave South,Room D5248 MCN, Nashville, TN 37232 USA
来源：
SEMINARS IN COLON AND RECTAL SURGERY | 2019年 / 30卷 / 02期
关键词：
Rectal cancer; Radiotherapy; Chemotherapy; Watch and wait; Non-operative management; QUALITY-OF-LIFE; COMPLETE CLINICAL-RESPONSE; LONG-TERM-OUTCOMES; EXTENDED NEOADJUVANT CHEMORADIATION; PREOPERATIVE CHEMORADIOTHERAPY; SEXUAL DYSFUNCTION; WAIT APPROACH; SEE POLICY; RESECTION; THERAPY;
D O I：
10.1053/j.scrs.2019.04.007
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Despite advances in technique, surgical resection of rectal cancer remains a morbid procedure that can lead to a profound decrease in a patient's quality of life. A novel method of management, termed "Non-operative management" (NOM), mirrors the management of anal carcinoma. Patients undergo definitive treatment with only chemotherapy and radiation, with resection reserved only for salvage. Current data is encouraging-both in reduction in morbidity and similar, if not superior oncologic results. However, there are a number of barriers to the wide adoption of this practice. This manuscript seeks to describe the rationale and execution of NOM as well as present the current data and pitfalls of the approach. (C) 2019 Elsevier Inc. All rights reserved.
引用
收藏
页码：79 / 84
页数：6
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