Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation

被引：6

作者：

Nakazawa, Yozo ^{[1
]}

Suzuki, Takefumi ^{[2
]}

Fukuyama, Tetsuhiro ^{[1
]}

Katsuyama, Yoshihiko ^{[3
]}

Tanaka, Miyuki ^{[1
]}

Yanagisawa, Ryu ^{[1
]}

Sakashita, Kazuo ^{[1
]}

Shiohara, Masaaki ^{[1
]}

Koike, Kenichi ^{[1
]}

机构：

[1] Shinshu Univ, Dept Pediat, Sch Med, Matsumoto, Nagano 3908621, Japan

[2] Shinshu Univ Hosp, Dept Lab Med, Matsumoto, Nagano, Japan

[3] Shinshu Univ Hosp, Dept Pharm, Matsumoto, Nagano, Japan

来源：

PEDIATRIC TRANSPLANTATION | 2009年 / 13卷 / 05期

关键词：

adenovirus; ganciclovir; hemorrhagic cystitis; stem-cell transplantation; STEM-CELL TRANSPLANTATION; INFECTION; RECIPIENTS; RIBAVIRIN; CIDOFOVIR; THERAPY; DISEASE; BLOOD;

D O I：

10.1111/j.1399-3046.2008.01027.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A nine-yr-old girl developed AdV-associated HC after bone marrow transplantation. Intravenous GCV markedly reduced urinary AdV DNA loads and improved clinical findings. This appeared to result partly from a high concentration of GCV in urine. GCV may be effective for AdV-induced HC without definitive disseminated infection.

引用

页码：632 / 635

页数：4

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