Prevalence, symptom patterns and management of episodic diarrhoea in the community: a population-based survey in 11 countries

被引:6
作者
Hungin, A. P. S. [1 ]
Paxman, L. [2 ]
Koenig, K. [3 ]
Dalrymple, J. [4 ]
Wicks, N. [5 ]
Walmsley, J. [3 ]
机构
[1] Univ Durham, Sch Med Pharm & Hlth, Wolfson Res Inst, Queens Campus, Stockton On Tees TS17 6BH, England
[2] Incite, London, England
[3] Johnson & Johnson Ltd, Maidenhead, Berks, England
[4] Univ E Anglia, Norwich Med Sch, Norwich NR4 7TJ, Norfolk, England
[5] Right Med Pharm Ltd, Stirling, Scotland
关键词
IRRITABLE-BOWEL-SYNDROME; WORKING TEAM REPORT; TRAVELERS DIARRHEA; PRIMARY-CARE; METAANALYSIS; GUIDELINES; DIAGNOSIS; ILLNESS; ADULTS; IMPACT;
D O I
10.1111/apt.13513
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
BackgroundThe extent of episodic diarrhoea in the community is relatively unknown. AimTo ascertain the prevalence, symptoms and management behaviours associated with self-reported diarrhoea across 11 countries. MethodsCommunity screening surveys were conducted using quota sampling of respondents to identify a nationally representative sample of individuals suffering from episodic' diarrhoea (occurring once a month or more often). Second-phase in-depth surveys provided data on epidemiology, symptoms, attributed causes and management of episodic diarrhoea. ResultsA total of 11 508 phase 1 and 6613 phase 2 surveys were completed. The prevalence of self-reported episodic diarrhoea ranged from 16% to 23% across the 11 countries. The majority of episodic diarrhoea sufferers were female (57%) and were not diagnosed with pre-existing irritable bowel syndrome (IBS); IBS diagnosis ranged from 9% in Mexico to 44% in Italy. Diarrhoea was frequently attributed to anxiety/stress, food-related causes, gastrointestinal sensitivity' and menstruation. Accompanying symptoms included stomach pain/cramping' (35-62%), stomach grumbling' (29-68%) and wind' (18-74%). The proportion of episodic sufferers who reported treating their symptoms with remedies or medications ranged between 46% in Belgium and Canada and 90% in Mexico. ConclusionsA substantial proportion of the population in middle- to high-income countries report episodic diarrhoea in the absence of a pre-existing diagnosis. These symptoms are likely to be associated with substantial social and economic costs, and have implications on how best to configure and guide self-led, pharmacist-led and primary care management.
引用
收藏
页码:586 / 595
页数:10
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