(1S,5R)-6,6-Dimethyl-4-(((1S,2S,5S)-2,6,6-trimethyl-4-oxobicyclo[3.1.1]heptan-2-yl)methyl)bicyclo[3.1.1]hept-3-en-2-one

被引：1

作者：

Ardashov, Oleg V. ^{[1
,2
]}

Korchagina, Dina V. ^{[1
]}

Bagryanskaya, Irina Yu. ^{[1
]}

Volcho, Konstantin P. ^{[1
]}

Salakhutdinov, Nariman F. ^{[1
]}

机构：

[1] Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Lavrentiev Ave 9, Novosibirsk 630090, Russia

[2] Novosibirsk State Univ, Dept Nat Sci, Pirogova Str 1, Novosibirsk 630090, Russia

来源：

MOLBANK | 2022年 / 2022卷 / 04期

基金：

俄罗斯基础研究基金会;

关键词：

verbenone; dimerization; extended enolate; Michael addition; VERBENONE;

D O I：

10.3390/M1465

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and convenient procedure for the gamma, beta-dimerization of verbenone was developed. The dimer was obtained during aging with KOH without a solvent. The process proceeds as the formation of the extended enolate of verbenone and its Michael addition to other molecules of verbenone. The product yield was 82% after purification by column chromatography and recrystallization.

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页数：4

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