Quality of Life and Health Care Use in Patients With Arthralgias Without Synovitis Compared With Patients Diagnosed With Early Rheumatoid Arthritis: Data From an Early Arthritis Cohort

被引:8
作者
Kuijper, T. Martijn [1 ]
Luime, Jolanda J. [1 ]
Alves, Celina [1 ]
Barendregt, Pieternella J. [2 ]
van Zeben, Jende [3 ]
Bindels, Patrick J. E. [1 ]
Hazes, Johanna M. W. [1 ]
机构
[1] Erasmus MC Univ Med Ctr, Rotterdam, Netherlands
[2] Maasstad Ziekenhuis, Rotterdam, Netherlands
[3] St Franciscus Gasthuis, Rotterdam, Netherlands
关键词
DISEASE-ACTIVITY; DEPRESSION SCALE; HOSPITAL ANXIETY; FATIGUE; CLASSIFICATION; METAANALYSIS; CRITERIA; SF-36;
D O I
10.1002/acr.22126
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectiveTo compare the burden of disease and its development over time in patients referred to an early arthritis cohort who were diagnosed either as having arthralgias without synovitis or as having rheumatoid arthritis (RA). MethodsPatients diagnosed as having arthralgias without synovitis or RA were selected from the Rotterdam Early Arthritis Cohort. Data on clinical and psychological characteristics, demographics, pain scores (Rheumatoid Arthritis Disease Activity Index), functional ability (Health Assessment Questionnaire), health-related quality of life (HRQOL; Short Form 36), fatigue (visual analog scale and Fatigue Assessment Scale), and health care utilization (HCU) were collected at baseline and at 6 and 12 months of followup. The burden of disease measures (pain, functional ability, fatigue, and HRQOL) and HCU levels were plotted over time for both groups. A Poisson regression model for repeated data was used to identify determinants of HCU for both groups. ResultsAt baseline, 330 patients with arthralgias without synovitis (nonsynovitis [NS] group) and 244 RA patients (RA group) were included. Overall, the burden of disease measures and HCU levels were very similar between groups. Both groups showed improvement over time with respect to pain scores, functional ability, HRQOL, and HCU levels. Independent predictors of high HCU were identified as more pain, worse physical health, and external locus of control in the NS group and as shorter duration of symptoms, low chance locus of control, and worse physical functioning in the RA group. ConclusionDespite the absence of an inflammatory diagnosis, patients with arthralgias without synovitis experienced a similar burden of disease compared with RA patients.
引用
收藏
页码:379 / 386
页数:8
相关论文
共 27 条
[1]   Translation, validation, and norming of the Dutch language version of the SF-36 Health Survey in community and chronic disease populations [J].
Aaronson, NK ;
Muller, M ;
Cohen, PDA ;
Essink-Bot, ML ;
Fekkes, M ;
Sanderman, R ;
Sprangers, MAG ;
Velde, AT ;
Verrips, E .
JOURNAL OF CLINICAL EPIDEMIOLOGY, 1998, 51 (11) :1055-1068
[2]   Treatment strategy, disease activity, and outcome in four cohorts of patients with early rheumatoid arthritis [J].
Albers, JMC ;
Paimela, L ;
Kurki, P ;
Eberhardt, KB ;
Emery, P ;
van't Hof, MA ;
Schreuder, FHJM ;
Leirisalo-Repo, M ;
van Riel, PLCM .
ANNALS OF THE RHEUMATIC DISEASES, 2001, 60 (05) :453-458
[3]   2010 Rheumatoid Arthritis Classification Criteria An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative [J].
Aletaha, Daniel ;
Neogi, Tuhina ;
Silman, Alan J. ;
Funovits, Julia ;
Felson, David T. ;
Bingham, Clifton O., III ;
Birnbaum, Neal S. ;
Burmester, Gerd R. ;
Bykerk, Vivian P. ;
Cohen, Marc D. ;
Combe, Bernard ;
Costenbader, Karen H. ;
Dougados, Maxime ;
Emery, Paul ;
Ferraccioli, Gianfranco ;
Hazes, Johanna M. W. ;
Hobbs, Kathryn ;
Huizinga, Tom W. J. ;
Kavanaugh, Arthur ;
Kay, Jonathan ;
Kvien, Tore K. ;
Laing, Timothy ;
Mease, Philip ;
Menard, Henri A. ;
Moreland, Larry W. ;
Naden, Raymond L. ;
Pincus, Theodore ;
Smolen, Josef S. ;
Stanislawska-Biernat, Ewa ;
Symmons, Deborah ;
Tak, Paul P. ;
Upchurch, Katherine S. ;
Vencovsky, Jiri ;
Wolfe, Frederick ;
Hawker, Gillian .
ARTHRITIS AND RHEUMATISM, 2010, 62 (09) :2569-2581
[4]   THE AMERICAN-RHEUMATISM-ASSOCIATION 1987 REVISED CRITERIA FOR THE CLASSIFICATION OF RHEUMATOID-ARTHRITIS [J].
ARNETT, FC ;
EDWORTHY, SM ;
BLOCH, DA ;
MCSHANE, DJ ;
FRIES, JF ;
COOPER, NS ;
HEALEY, LA ;
KAPLAN, SR ;
LIANG, MH ;
LUTHRA, HS ;
MEDSGER, TA ;
MITCHELL, DM ;
NEUSTADT, DH ;
PINALS, RS ;
SCHALLER, JG ;
SHARP, JT ;
WILDER, RL ;
HUNDER, GG .
ARTHRITIS AND RHEUMATISM, 1988, 31 (03) :315-324
[5]   Self-reported utilization of health care services: Improving measurement and accuracy [J].
Bhandari, A ;
Wagner, T .
MEDICAL CARE RESEARCH AND REVIEW, 2006, 63 (02) :217-235
[6]   The validity of the Hospital Anxiety and Depression Scale - An updated literature review [J].
Bjelland, I ;
Dahl, AA ;
Haug, TT ;
Neckelmann, D .
JOURNAL OF PSYCHOSOMATIC RESEARCH, 2002, 52 (02) :69-77
[7]   Effect of biotherapies on fatigue in rheumatoid arthritis: a systematic review of the literature and meta-analysis [J].
Chauffier, Karine ;
Salliot, Carine ;
Berenbaum, Francis ;
Sellam, Jeremie .
RHEUMATOLOGY, 2012, 51 (01) :60-68
[8]  
Cush JJ, 2007, J RHEUMATOL, V34, P1
[9]   Long-term impact of early treatment on radiographic progression in rheumatoid arthritis: A meta-analysis [J].
Finckh, Axel ;
Liang, Matthew H. ;
van Herckenrode, Carmen Mugica ;
de Pablo, Paola .
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH, 2006, 55 (06) :864-872
[10]   MEASUREMENT OF PATIENT OUTCOME IN ARTHRITIS [J].
FRIES, JF ;
SPITZ, P ;
KRAINES, RG ;
HOLMAN, HR .
ARTHRITIS AND RHEUMATISM, 1980, 23 (02) :137-145