Risk factors for surgical site infection in Japanese patients with ulcerative colitis: a multicenter prospective study

被引:17
作者
Araki, Toshimitsu [1 ]
Okita, Yoshiki [1 ]
Uchino, Motoi [2 ]
Ikeuchi, Hiroki [3 ]
Sasaki, Iwao [4 ]
Funayama, Yuji [5 ]
Fukushima, Kouhei [6 ]
Futami, Kitarou [7 ]
Maeda, Kiyoshi [8 ]
Iiai, Tsuneo [9 ]
Itabashi, Michio [10 ]
Hase, Kazuo [11 ]
Motoya, Satoshi [12 ]
Kitano, Atsuo [13 ]
Mizushima, Tsunekazu [14 ]
Maeda, Kotaro [15 ]
Kobayashi, Minako [16 ]
Mohri, Yasuhiko [1 ]
Kusunoki, Masato [1 ,2 ]
机构
[1] Mie Univ, Grad Sch Med, Dept Gastrointestinal & Pediat Surg, Div Reparat Med,Inst Life Sci, Tsu, Mie 5148507, Japan
[2] Hyogo Coll Med, Dept Lower Gastroenterol Surg, Nishinomiya, Hyogo 6638501, Japan
[3] Hyogo Coll Med, Ctr Inflammatory Bowel Dis, Nishinomiya, Hyogo 6638501, Japan
[4] Tohoku Univ, Dept Surg, Grad Sch Med, Sendai, Miyagi 980, Japan
[5] Tohoku Rosai Hosp, Dept Colorectal Surg, Sendai, Miyagi, Japan
[6] Tohoku Univ, Grad Sch Med, Div Mol & Surg Pathophysiol, Sendai, Miyagi 980, Japan
[7] Fukuoka Univ, Chikushi Hosp, Dept Surg, Chikushino, Japan
[8] Osaka City Univ, Dept Surg Oncol, Grad Sch Med, Osaka 558, Japan
[9] Niigata Univ, Grad Sch Med & Dent Sci, Div Digest & Gen Surg, Niigata, Japan
[10] Tokyo Womens Med Univ, Dept Surg 2, Tokyo, Japan
[11] Natl Def Med Coll, Dept Surg, Tokorozawa, Saitama 359, Japan
[12] Sapporo Kosei Gen Hosp, IBD Ctr, Sapporo, Hokkaido, Japan
[13] Wakakusa First Hosp, Dept Gastroenterol, Osaka, Japan
[14] Osaka Univ, Dept Surg, Grad Sch Med, Suita, Osaka, Japan
[15] Fujita Hlth Univ, Sch Med, Dept Surg, Toyoake, Aichi 47011, Japan
[16] Mie Univ, Grad Sch Med, Dept Innovat Surg & Surg Tech Dev, Tsu, Mie 5148507, Japan
关键词
Ulcerative colitis; Surgical site infection; Complication; Multicenter surveillance; MECHANICAL BOWEL PREPARATION; COLORECTAL SURGERY; POSTOPERATIVE COMPLICATIONS; PREVENTION; COLON; HOSPITALIZATION; METAANALYSIS; ANASTOMOSIS; MORTALITY; IMPACT;
D O I
10.1007/s00595-013-0809-9
中图分类号
R61 [外科手术学];
学科分类号
摘要
A prospective, multicenter, observational study was performed to investigate the risk factors of surgical site infection (SSI) in patients with ulcerative colitis (UC). From 2009 to 2010, perioperative clinicopathological data were collected from patients who had undergone surgery for UC within the research period, for up to 6 consecutive months in 13 hospitals in Japan. The primary outcome was the development of SSI. A total of 195 patients with UC who underwent colorectal surgery were enrolled. SSI was diagnosed in 38 (19.5 %) patients, in the form of incisional infection in 23 (11.8 %), organ/space infection in 16 (8.2 %), and both in 1 (0.5 %). There were no significant risk factors associated with an increased risk of development of incisional SSI. An American Society of Anesthesiologists physical status of a parts per thousand yen 3 was indicated as the only significant risk factor for organ/space SSI (P = 0.02) compared with other factors, such as a neutrophil count of > 100 x 10(2)/mm(3), albumin level of < 3.5 g/dl, perioperative packed red blood cell transfusion, fair or poor colonic cleanliness, and therapeutic use of antibiotics. Poor general physical status was the significant independent risk factor for organ/space SSI in patients with UC in Japan.
引用
收藏
页码:1072 / 1078
页数:7
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