Long-term follow-up of ETV6-RUNX1 ALL reveals that NCI risk, rather than secondary genetic abnormalities, is the key risk factor

被引：22

作者：

Enshaei, A. ^{[1
]}

Schwab, C. J. ^{[1
]}

Konn, Z. J. ^{[1
]}

Mitchell, C. D. ^{[2
]}

Kinsey, S. E. ^{[3
,4
]}

Wade, R. ^{[5
]}

Vora, A. ^{[6
]}

Harrison, C. J. ^{[1
]}

Moorman, A. V. ^{[1
]}

机构：

[1] Newcastle Univ, Northern Inst Canc Res, Leukaemia Res Cytogenet Grp, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England

[2] John Radcliffe Hosp, Dept Paediat Oncol, Oxford OX3 9DU, England

[3] Leeds Gen Infirm, Dept Paediat Haematol & Oncol, Leeds, W Yorkshire, England

[4] Univ Leeds, Leeds Inst Mol Med, Leeds, W Yorkshire, England

[5] Univ Oxford, Clin Trial Serv Unit, Oxford, England

[6] Sheffield Childrens Hosp, Dept Haematol, Sheffield, S Yorkshire, England

来源：

LEUKEMIA | 2013年 / 27卷 / 11期

基金：

英国医学研究理事会;

关键词：

ACUTE LYMPHOBLASTIC-LEUKEMIA; REARRANGEMENTS; PROTOCOL; IMPACT; ETV6; TEL;

D O I：

10.1038/leu.2013.136

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：2256 / 2259

页数：5

共 15 条

[1] Abnormalities of the der(12)t(12;21) in ETV6-RUNX1 acute lymphoblastic leukemia [J].

Al-Shehhi, Halima ;

Konn, Zoe J. ;

Schwab, Claire J. ;

Erhorn, Amy ;

Barber, Kerry E. ;

Wright, Sarah L. ;

Gabriel, Alem S. ;

Harrison, Christine J. ;

Moorman, Anthony V. .

GENES CHROMOSOMES & CANCER, 2013, 52 (02) :202-213

[2] Incidence and relevance of secondary chromosome abnormalities in childhood TEL/AML1+ acute lymphoblastic leukemia:: an interphase FISH analysis [J].

Attarbaschi, A ;

Mann, G ;

König, M ;

Dworzak, MN ;

Trebo, MM ;

Mühlegger, N ;

Gadner, H ;

Haas, OA .

LEUKEMIA, 2004, 18 (10) :1611-1616

[3] Additional aberrations of the ETV6 and RUNX1 genes have no prognostic impact in 229 t(12;21)(p13;q22)-positive B-cell precursor acute lymphoblastic leukaemias treated according to the NOPHO-ALL-2000 protocol [J].

Barbany, Gisela ;

Andersen, Mette K. ;

Autio, Kirsti ;

Borgstrom, Georg ;

Franco, Lucia Cavalier ;

Golovleva, Irina ;

Heim, Sverre ;

Heinonen, Kristina ;

Hovland, Randi ;

Johansson, Bertil ;

Johannsson, Johann H. ;

Kjeldsen, Eigil ;

Nordgren, Ann ;

Palmqvist, Lars ;

Forestier, Erik .

LEUKEMIA RESEARCH, 2012, 36 (07) :936-938

[4] ETV6-RUNX1-positive childhood acute lymphoblastic leukemia: improved outcome with contemporary therapy [J].

Bhojwani, D. ;

Pei, D. ;

Sandlund, J. T. ;

Jeha, S. ;

Ribeiro, R. C. ;

Rubnitz, J. E. ;

Raimondi, S. C. ;

Shurtleff, S. ;

Onciu, M. ;

Cheng, C. ;

Coustan-Smith, E. ;

Bowman, W. P. ;

Howard, S. C. ;

Metzger, M. L. ;

Inaba, H. ;

Leung, W. ;

Evans, W. E. ;

Campana, D. ;

Relling, M. V. ;

Pui, C-H .

LEUKEMIA, 2012, 26 (02) :265-270

[5] Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study [J].

Borowitz, Michael J. ;

Devidas, Meenakshi ;

Hunger, Stephen P. ;

Bowman, W. Paul ;

Carroll, Andrew J. ;

Carroll, William L. ;

Linda, Stephen ;

Martin, Paul L. ;

Pullen, D. Jeanette ;

Viswanatha, David ;

Willman, Cheryl L. ;

Winick, Naomi ;

Camitta, Bruce M. .

BLOOD, 2008, 111 (12) :5477-5485

[6] Outcome of ETV6/RUNX1-positive childhood acute lymphoblastic leukaemia in the NOPHO-ALL-1992 protocol:: frequent late relapses but good overall survival [J].

Forestier, Erik ;

Heyman, Mats ;

Andersen, Mette K. ;

Autio, Kirsi ;

Blennow, Elisabeth ;

Borgstrom, Georg ;

Golovleva, Irina ;

Heim, Sverre ;

Heinonen, Kristina ;

Hovland, Randi ;

Johannsson, Johann H. ;

Kerndrup, Gitte ;

Nordgren, Ann ;

Rosenquist, Richard ;

Swolin, Birgitta ;

Johansson, Bertil .

BRITISH JOURNAL OF HAEMATOLOGY, 2008, 140 (06) :665-672

[7] Cytogenetic patterns in ETV6/RUNXI-positive pediatric B-cell precursor acute lymphoblastic leukemia:: A Nordic series of 245 cases and review of the literature [J].

Forestier, Erik ;

Andersen, Mette K. ;

Autio, Kirsi ;

Blennow, Elisabeth ;

Borgstrom, Georg ;

Golovleva, Irina ;

Heim, Sverre ;

Heinonen, Kristina ;

Hovland, Randi ;

Johannsson, Johann H. ;

Kerndrup, Gitte ;

Nordgren, Ann ;

Rosenquist, Richard ;

Swolin, Birgitta ;

Johansson, Bertil .

GENES CHROMOSOMES & CANCER, 2007, 46 (05) :440-450

[8] Native ETV6 deletions accompanied by ETV6-RUNX1 rearrangements are associated with a favourable prognosis in childhood acute lymphoblastic leukaemia: a candidate for prognostic marker [J].

Ko, Dae-Hyun ;

Jeon, Yongbum ;

Kang, Hyoung Jin ;

Park, Kyung Duk ;

Shin, Hee Young ;

Kim, Hyun Kyung ;

Cho, Han-Ik ;

Ahn, Hyo Seop ;

Lee, Dong Soon .

BRITISH JOURNAL OF HAEMATOLOGY, 2011, 155 (04) :530-533

[9] Prognostic value of genetic alterations in children with first bone marrow relapse of childhood B-cell precursor acute lymphoblastic leukemia [J].

Krentz, S. ;

Hof, J. ;

Mendioroz, A. ;

Vaggopoulou, R. ;

Doerge, P. ;

Lottaz, C. ;

Engelmann, J. C. ;

Groeneveld, T. W. L. ;

Koerner, G. ;

Seeger, K. ;

Hagemeier, C. ;

Henze, G. ;

Eckert, C. ;

von Stackelberg, A. ;

Kirschner-Schwabe, R. .

LEUKEMIA, 2013, 27 (02) :295-304

[10] Prospective analysis of TEL/AML1-positive patients treated on Dana-Farber Cancer Institute consortium protocol 95-01 [J].

Loh, Mignon L. ;

Goldwasser, Meredith A. ;

Silverman, Lewis B. ;

Poon, Wing-Man ;

Vattikuti, Shashaank ;

Cardoso, Angelo ;

Neuberg, Donna S. ;

Shannon, Kevin M. ;

Sallan, Stephen E. ;

Gilliland, D. Gary .

BLOOD, 2006, 107 (11) :4508-4513

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