High Nasal Burden of Methicillin-Resistant Staphylococcus aureus Increases Risk of Invasive Disease

被引:24
作者
Datta, Rupak [1 ]
Shah, Atia [2 ]
Huang, Susan S. [1 ,2 ]
Cui, Eric [1 ,2 ]
Vinh Nguyen [3 ]
Welbourne, Susan J. [4 ]
Quan, Kathleen A. [5 ]
Thrupp, Lauri [2 ]
机构
[1] Univ Calif Irvine, Sch Med, Hlth Policy Res Inst, Irvine, CA 92717 USA
[2] Univ Calif Irvine, Div Infect Dis, Med Ctr, Irvine, CA USA
[3] Univ Calif Irvine, Dept Stat, Irvine, CA USA
[4] Univ Calif Irvine, Dept Decis Support Serv, Med Ctr, Irvine, CA USA
[5] Univ Calif Irvine, Dept Epidemiol & Infect Prevent, Med Ctr, Irvine, CA USA
关键词
SURGICAL-SITE INFECTIONS; BACTEREMIA; COLONIZATION; MUPIROCIN; CARRIAGE; CARRIERS; ASSOCIATION; SURGERY;
D O I
10.1128/JCM.01606-13
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In a retrospective cohort study of 1,140 patients harboring methicillin-resistant Staphylococcus aureus, the nasal burden was low in 31%, category 1+ to 2+ in 54%, and category 3+ to 4+ in 15%. There was a significant trend in infection risk with increasing nasal burden (P = 0.007). In multivariate models, high nasal burden remained significantly associated with invasive infection.
引用
收藏
页码:312 / 314
页数:3
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