Oral findings in Williams-Beuren syndrome

被引：11

作者：

Ferreira, Shirlene-Barbosa-Pimentel ^{[1
]}

Viana, Melissa-Machado ^{[2
]}

Maia, Naiara-Goncalves-Fonseca ^{[1
]}

Leao, Leticia-Lima ^{[2
]}

Machado, Renato-Assis ^{[3
]}

Ricardo-Della Coletta ^{[3
]}

de Aguiar, Marcos-Jose-Burle ^{[2
]}

Martelli-Junior, Hercilio ^{[1
,4
]}

机构：

[1] Univ Estadual Montes Claros, Hlth Sci Program, Unimontes, Montes Claros, MG, Brazil

[2] Univ Fed Minas Gerais, Clin Genet Serv, UFMG, Belo Horizonte, MG, Brazil

[3] Piracicaba Dent Sch FOP Unicamp, Dept Oral Diag, Piracicaba, SP, Brazil

[4] Univ Estadual Montes Claros, Dent Sch, Stomatol Clin, Unimontes, Montes Claros, MG, Brazil

来源：

MEDICINA ORAL PATOLOGIA ORAL Y CIRUGIA BUCAL | 2018年 / 23卷 / 01期

关键词：

Congenital abnormalities; Orofacial features; Williams-Beuren syndrome; PHENOTYPE; DELETIONS; GENES;

D O I：

10.4317/medoral.21834

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Background: Williams-Beuren syndrome (WBS; OMIM #194050) is a developmental disorder characterized by congenital heart disease, intellectual disability, dysmorphic facial features and ophthalmologic abnormalities. Oral abnormalities are also described in clinical manifestations of the disease. This paper describes orofacial features in patients with WBS. Material and Methods: Seventeen patients with a confirmed molecular diagnosis of WBS were examined for oral abnormalities through clinical oral evaluations and panoramic radiography. Results: Malocclusion, specifically with dental midline deviation, and high-arched palate were the most common findings. Conclusions: The present results contribute to knowledge on the orofacial manifestations of WBS. Since such patients with WBS may develop severe oral abnormalities, early detection and treatment can help improve their quality of life.

引用

页码：E1 / E6

页数：6

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