Gram-Negative Skin and Soft Tissue Infections

被引:19
作者
Jabbour, Jean-Francois [1 ]
Kanj, Souha S. [1 ]
机构
[1] Amer Univ Beirut, Med Ctr, Dept Internal Med, Div Infect Dis, POB 11-0236, Beirut 11072020, Lebanon
关键词
Gram-negative; Skin and soft tissue infections; Epidemiology; Diagnosis; Treatment; COMPLICATED SKIN; ACINETOBACTER-BAUMANNII; RESISTANT; MANAGEMENT; MULTIDRUG; DIAGNOSIS; BACTERIA; CEFTAZIDIME/AVIBACTAM; EPIDEMIOLOGY; COMBINATION;
D O I
10.1016/j.idc.2020.10.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Skin and soft tissue infections (SSTIs) frequently are encountered in clinical practice, and gram-negative bacilli (GNB) constitute an underrated portion of their etiology. The rate of GNB-causing SSTIs is increasing, especially with the rise in antimicrobial resistance. Although the diagnosis of SSTIs mostly is clinical, rapid diagnostic modalities can shorten the time to initiating proper therapy and improving outcomes. Novel antibiotics are active against GNB SSTIs and can be of great value in the management. This review provides an overview of the role of GNB in SSTIs and summarizes their epidemiology, risk factors, outcome, and clinical management. © 2020 Elsevier Inc.
引用
收藏
页码:157 / 167
页数:11
相关论文
共 44 条
[1]   Post-surgical mediastinitis due to carbapenem-resistant Enterobacteriaceae: Clinical, epidemiological and survival characteristics [J].
Abboud, C. S. ;
Monteiro, J. ;
Stryjewski, M. E. ;
Zandonadi, E. C. ;
Barbosa, V. ;
Dantas, D. ;
Sousa, E. E. ;
Fonseca, M. J. ;
Jacobs, D. M. ;
Pignatari, A. C. ;
Kiffer, C. ;
Rao, G. G. .
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2016, 47 (05) :386-390
[2]   Fatal skin and soft tissue infection of multidrug resistant Acinetobacter baumannii: A case report [J].
Ali, Aqsa ;
Botha, John ;
Tiruvoipati, Ravindranath .
INTERNATIONAL JOURNAL OF SURGERY CASE REPORTS, 2014, 5 (08) :532-536
[3]   PET/CT Imaging in Soft Tissue Infection and Inflammation-An Update [J].
Arnon-Sheleg, Elite ;
Israel, Ora ;
Keidar, Zohar .
SEMINARS IN NUCLEAR MEDICINE, 2020, 50 (01) :35-49
[4]   Surgical site infection in critically ill patients with secondary and tertiary peritonitis: epidemiology, microbiology and influence in outcomes [J].
Ballus, Josep ;
Lopez-Delgado, Juan C. ;
Sabater-Riera, Joan ;
Perez-Fernandez, Xose L. ;
Betbese, A. J. ;
Roncal, J. A. .
BMC INFECTIOUS DISEASES, 2015, 15
[5]   Patient specific risk stratification for antimicrobial resistance and possible treatment strategies in gram-negative bacterial infections [J].
Bassetti, Matteo ;
Carnelutti, Alessia ;
Peghin, Maddalena .
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY, 2017, 15 (01) :55-65
[6]   The role of multidrug and extensive-drug resistant Gam-negative bacteria in skin and soft tissue infections [J].
Brink, Adrian J. ;
Richards, Guy A. .
CURRENT OPINION IN INFECTIOUS DISEASES, 2020, 33 (02) :93-100
[7]   Ceftazidime-avibactam or best available therapy in patients with ceftazidime-resistant Enterobacteriaceae and Pseudomonas aeruginosa complicated urinary tract infections or complicated intra-abdominal infections (REPRISE): a randomised, pathogen-directed, phase 3 study [J].
Carmeli, Yehuda ;
Armstrong, Jon ;
Laud, Peter J. ;
Newell, Paul ;
Stone, Greg ;
Wardman, Angela ;
Gasink, Leanne B. .
LANCET INFECTIOUS DISEASES, 2016, 16 (06) :661-673
[8]  
Del Giacomo P, 2019, CURR OPIN INFECT DIS, V32, P113, DOI [10.1097/QCO.0000000000000528, 10.1097/qco.0000000000000528]
[9]   Complicated skin and soft tissue infection [J].
Dryden, Matthew S. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2010, 65 :iii35-iii44
[10]  
Eckman C, 2010, EUR J MED RES, V15, P554