Enhanced simultaneous electroanalytical determination of two fluoroquinolones by using surfactant media and a peak deconvolution procedure

被引：28

作者：

Bilibio, Uendinara ^{[1
]}

de Oliveira, Luiz Henrique ^{[1
]}

Ferreira, Valdir Souza ^{[2
]}

Goncalves Trindade, Magno Aparecido ^{[1
]}

机构：

[1] Fed Univ Grande Dourados, Fac Sci & Technol, BR-79804970 Dourados, MS, Brazil

[2] Univ Fed Mato Grosso, Inst Chem, BR-79074460 Campo Grande, MS, Brazil

来源：

MICROCHEMICAL JOURNAL | 2014年 / 116卷

关键词：

Fluoroquinolones; Deconvolution procedure; Micellar media; Electroanalysis; ANODIC-STRIPPING VOLTAMMETRY; VETERINARY DRUG RESIDUES; CARBON-PASTE ELECTRODE; HUMAN URINE; SENSITIVE DETERMINATION; LEVOFLOXACIN; NORFLOXACIN; SUPPRESSION; INTERFERENCES; CIPROFLOXACIN;

D O I：

10.1016/j.microc.2014.04.009

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of anionic surfactants and the application of a deconvolution procedure were investigated as suitable methods to provide electrochemical peak separation in the simultaneous detection of the fluoroquinolones levofloxacin (LEVO) and norfloxacin (NOR). Concurrently, an electroanalytical methodology was developed based on the simultaneous determination of both fluoroquinolones using a mathematical treatment via baseline correction. We also developed a deconvolution procedure to separate overlapping peaks. These methods provided satisfactory peak separation and intensification of peak current, allowing efficient quantification of analytes in both tablets and biological samples with recovery values ranging from 88.1%-107.5%. (C) 2014 Elsevier B.V. All rights reserved.

引用

页码：47 / 54

页数：8

共 43 条

[1]

[Anonymous], 1993, Statistics for Analytical Chemistry

[2] Efficacy and safety of Levofloxacin in the context of other contemporary fluoroquinolones: A review [J].

Ball, P .

CURRENT THERAPEUTIC RESEARCH-CLINICAL AND EXPERIMENTAL, 2003, 64 (09) :646-661

[3] Determination of the antibiotic drug pefloxacin in bulk form, tablets and human serum using square wave cathodic adsorptive stripping voltammetry [J].

Beltagi, AM .

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2003, 31 (06) :1079-1088

[4]

Blondeau JM, 1999, CLIN THER, V21, P3

[5] The Newer Fluoroquinolones [J].

Bolon, Maureen K. .

MEDICAL CLINICS OF NORTH AMERICA, 2011, 95 (04) :793-+

[6] A new voltammetric method for the simultaneous determination of the antioxidants TBHQ and BHA in biodiesel using multi-walled carbon nanotube screen-printed electrodes [J].

Caramit, Ricardo Pini ;

de Freitas Andrade, Adriana Garabini ;

Gomes de Souza, Joao Batista ;

de Araujo, Tatiane Alfonso ;

Viana, Luiz Henrique ;

Goncalves Trindade, Magno Aparecido ;

Ferreira, Valdir Souza .

FUEL, 2013, 105 :306-313

[7]

Cardoso J.C., 2008, COLLOIDS SURF B, V63

[8] Evaluation of veterinary drug residues in food for their potential to affect human intestinal microflora [J].

Cerniglia, CE ;

Kotarski, S .

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1999, 29 (03) :238-261

[9] Polarographic determination of sunscreen agents in cosmetic products in micellar media [J].

da Silva, AP ;

Trindade, MAG ;

Ferreira, VS .

TALANTA, 2006, 68 (03) :679-685

[10] Exploiting micellar environment for simultaneous electrochemical determination of ascorbic acid and dopamine [J].

dos Reis, AP ;

Tarley, CRT ;

Maniasso, N ;

Kubota, LT .

TALANTA, 2005, 67 (04) :829-835

← 1 2 3 4 5 →