Carbon-centered radicals add reversibly to histidine - implications

被引：12
|
作者：
Nauser, Thomas [1 ]
Carreras, Anna [1 ]
机构：
[1] ETH, Anorgan Chem Lab, Dept Chem & Angew Biowissensch, CH-8093 Zurich, Switzerland
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 92期
关键词：
CYSTEINE THIYL RADICALS; PULSE-RADIOLYSIS; REDOX POTENTIALS; PROTEIN RADICALS; REDUCTION; PEPTIDES; TRYPTOPHAN; TYROSINE;
D O I：
10.1039/c4cc05316h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Carbon-centered radicals of alcohols commonly used as hydroxyl radical scavengers (MeOH, EtOH, i-PrOH and t-BuOH) add reversibly to histidine with equilibrium constants up to 3 x 10(3) M-1 and rate constants on the order of 10(9) M-1 s(-1). Similar equilibria may compromise determinations of one-electron (radical) electrode potentials.
引用
收藏
页码：14349 / 14351
页数：3
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